Gene Symbol | HCFC1R1 |
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Entrez Gene | 54985 |
Alt Symbol | HPIP |
Species | Human |
Gene Type | protein-coding |
Description | host cell factor C1 regulator 1 (XPO1 dependent) |
Other Description | HCF-1 beta-propeller-interacting protein|host cell factor C1 regulator 1 |
Swissprots | Q68EN7 D3DUA7 Q9NWW0 |
Accessions | CAV30734 CAV30735 CAV30736 EAW85424 EAW85425 EAW85426 EAW85427 Q9NWW0 AK000575 BAA91265 AK293768 BAG57184 AY116892 AAM49798 BC064026 AAH64026 BC065514 BC080178 AAH80178 BM790570 BM925785 BU623445 BU633901 CN427571 CR457245 CAG33526 HQ447528 ADQ32014 XM_011522558 XP_011520860 XM_011522559 XP_011520861 NM_001002017 NP_001002017 NM_001002018 NP_001002018 NM_001288665 NP_001275594 NM_001288666 NP_001275595 NM_001288667 NP_001275596 NM_001288668 NP_001275597 NM_001308070 NP_001294999 NM_017885 NP_060355 |
Function | Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus. {ECO:0000269|PubMed:12235138}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:12235138}. Nucleus {ECO:0000269|PubMed:12235138}. Note=Shuttles between the nucleus and cytoplasm in a CRM1-dependent manner. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:12235138}. |
HCFC1R1-Over-expression-Lysate - LY15959a from Abgent, a WuXi AppTec company
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HCFC1R1 overexpression lysate - LY413468 from Acris Antibodies
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HCFC1R1 overexpression lysate - LY424320 from Acris Antibodies
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HCFC1R1 overexpression lysate - LY424321 from Acris Antibodies
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HCFC1R1 overexpression lysate - LY425070 from Acris Antibodies
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HCFC1R1 293 Cell Lysate - 406509 from ABBIOTEC
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HCFC1R1 293 Cell Lysate - 410052 from ABBIOTEC
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HCFC1R1 Overexpression Lysate (Native) - NBL1-11468 from Novus Biologicals
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HCFC1R1 Overexpression Lysate (Native) - NBP2-09087 from Novus Biologicals
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HCFC1R1 Overexpression Lysate (Native) - NBP2-08974 from Novus Biologicals
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HCFC1R1 Overexpression Lysate (Native) - NBP2-08973 from Novus Biologicals
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HCFC1R1 Over-expression Lysate Product - GWB-EBE034 from Genway Biotech
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HCFC1R1 Over-expression Lysate Product - GWB-B8B3F1 from Genway Biotech
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Panoply™ Human HCFC1R1 Knockdown Stable Cell Line - CSC-DC006872 from Creative biogene
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HCFC1R1 KO Cell Lysate-HEK293T - CLKO-0729 from Creative biogene
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