Gene Symbol | HCFC1R1 |
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Entrez Gene | 54985 |
Alt Symbol | HPIP |
Species | Human |
Gene Type | protein-coding |
Description | host cell factor C1 regulator 1 (XPO1 dependent) |
Other Description | HCF-1 beta-propeller-interacting protein|host cell factor C1 regulator 1 |
Swissprots | Q68EN7 D3DUA7 Q9NWW0 |
Accessions | CAV30734 CAV30735 CAV30736 EAW85424 EAW85425 EAW85426 EAW85427 Q9NWW0 AK000575 BAA91265 AK293768 BAG57184 AY116892 AAM49798 BC064026 AAH64026 BC065514 BC080178 AAH80178 BM790570 BM925785 BU623445 BU633901 CN427571 CR457245 CAG33526 HQ447528 ADQ32014 XM_011522558 XP_011520860 XM_011522559 XP_011520861 NM_001002017 NP_001002017 NM_001002018 NP_001002018 NM_001288665 NP_001275594 NM_001288666 NP_001275595 NM_001288667 NP_001275596 NM_001288668 NP_001275597 NM_001308070 NP_001294999 NM_017885 NP_060355 |
Function | Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus. {ECO:0000269|PubMed:12235138}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:12235138}. Nucleus {ECO:0000269|PubMed:12235138}. Note=Shuttles between the nucleus and cytoplasm in a CRM1-dependent manner. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:12235138}. |
HCFC1R1 CRISPR/Cas9 KO Plasmid (h) - sc-407323 from Santa Cruz Biotechnology
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HCFC1R1 HDR Plasmid (h) - sc-407323-HDR from Santa Cruz Biotechnology
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HCFC1R1 Double Nickase Plasmid (h) - sc-407323-NIC from Santa Cruz Biotechnology
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HCFC1R1 Double Nickase Plasmid (h2) - sc-407323-NIC-2 from Santa Cruz Biotechnology
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HCFC1R1 CRISPR Activation Plasmid (h) - sc-407323-ACT from Santa Cruz Biotechnology
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HCFC1R1 CRISPR Activation Plasmid (h2) - sc-407323-ACT-2 from Santa Cruz Biotechnology
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HCFC1R1 Lentiviral Activation Particles (h) - sc-407323-LAC from Santa Cruz Biotechnology
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HCFC1R1 Lentiviral Activation Particles (h2) - sc-407323-LAC-2 from Santa Cruz Biotechnology
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HCFC1R1 siRNA (h) - sc-93241 from Santa Cruz Biotechnology
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HCFC1R1 shRNA Plasmid (h) - sc-93241-SH from Santa Cruz Biotechnology
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HCFC1R1 shRNA (h) Lentiviral Particles - sc-93241-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN9912 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9912 from Sigma-Aldrich
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HCFC1R1 siRNA (Human) - CRJ0382 from Cohesion Biosciences
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HCFC1R1 - MBS8221050 from MyBioSource
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shRNA set against Human HCFC1R1 (NM_017885.2) - SHH310757 from Creative biogene
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shRNA set against Human HCFC1R1(NM_001002017.1) - SHH115283 from Creative biogene
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shRNA set against Human HCFC1R1(NM_001002018.1) - SHH115301 from Creative biogene
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Human HCFC1R1 siRNA - orb270883 from Biorbyt
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HCFC1R1 shRNA Plasmid (Human) - CHJ0382 from Cohesion Biosciences
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HCFC1R1 miRNA 3'UTR clone - MiUTR1H-04395 from Creative biogene
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HCFC1R1 miRNA 3'UTR clone - MiUTR1H-04396 from Creative biogene
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HCFC1R1 miRNA 3'UTR clone - MiUTR3H-15077 from Creative biogene
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