Gene Symbol | AKR7A3 |
---|---|
Entrez Gene | 22977 |
Alt Symbol | AFAR2 |
Species | Human |
Gene Type | protein-coding |
Description | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) |
Other Description | AFB1 aldehyde reductase 2|AFB1-AR 2|aflatoxin B1 aldehyde reductase 2|aflatoxin B1 aldehyde reductase member 3 |
Swissprots | Q9NUC3 O95154 Q8N5V6 Q8TAX1 Q86SR4 Q8IVN6 |
Accessions | EAW94878 EAW94879 O95154 AA844782 AF040639 AAD02195 AJ271799 CAC81076 BC025709 AAH25709 BC031562 AAH31562 BC042420 AAH42420 BG747063 BM855386 BM920315 EU176235 ABW03686 EU176541 ABW03342 EU831806 ACE87324 EU831883 ACE86642 XM_011541046 XP_011539348 XM_011541047 XP_011539349 NM_012067 NP_036199 |
Function | Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. {ECO:0000269|PubMed:18416522}. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium. {ECO:0000269|PubMed:12879023, ECO:0000269|PubMed:18416522}. |
Top Pathways | Metabolism of xenobiotics by cytochrome P450 |
Anti-AKR7A3 antibody - ab85135 from Abcam
|
||||||||||
Anti-AKR7A3 antibody - ab68573 from Abcam
|
||||||||||
Anti-AKR7A3 antibody [AT2E1] - ab128599 from Abcam
|
||||||||||
Anti-AKR7A3 antibody [AT2E11] - ab178507 from Abcam
|
||||||||||
Anti-AKR7A3 Antibody - LS-C306190 from LifeSpan Bioscience
|
||||||||||
Anti-AKR7A3 Antibody (aa179-228) - LS-C110890 from LifeSpan Bioscience
|
||||||||||
Anti-AKR7A3 Antibody (Internal) - LS-C137134 from LifeSpan Bioscience
|
||||||||||
Anti-AKR7A3 Antibody (clone AT2E11) IHC-plus⢠- LS-B8967 from LifeSpan Bioscience
|
||||||||||
AKR7A3 Antibody - NBP1-31614 from Novus Biologicals
|
||||||||||
AKR7A3 Antibody - NBP1-56768 from Novus Biologicals
|
||||||||||
AKR7A3 Antibody (2E11) - NBP1-97944 from Novus Biologicals
|
||||||||||
AKR7A3 Antibody - H00022977-B01P from Novus Biologicals
|
||||||||||
Anti-AKR7A3 antibody produced in rabbit - SAB2103216 from Sigma-Aldrich
|
||||||||||
Anti-AKR7A3 antibody produced in mouse - SAB1400435 from Sigma-Aldrich
|
||||||||||
AKR7A3 Antibody (OALA07315) - OALA07315 from Aviva Systems Biology
|
||||||||||
AKR7A3 antibody - middle region (ARP54824_P050) - ARP54824_P050 from Aviva Systems Biology
|
||||||||||
AKR7A3 antibody [AT2E11] - GTX53685 from GeneTex
|
||||||||||
AKR7A3 antibody [N3C3] - GTX106613 from GeneTex
|
||||||||||
Anti -AKR7A3 (Aflatoxin B1 Aldehyde Reductase Member 3, AFB1 Aldehyde Reductase 2, AFB1-AR2, AFAR2) - 045405 from USBiological Life Science
|
||||||||||
Anti -AKR7A3 (Aflatoxin B1 Aldehyde Reductase Member 3, AFB1 Aldehyde Reductase 2, AFB1-AR2, AFAR2) - 123178 from USBiological Life Science
|
||||||||||
AKR7A3 antibody - orb77427 from Biorbyt
|
||||||||||
AKR7A3 antibody - 10R-3135 from Fitzgerald
|
||||||||||
AKR7A3 antibody - 70R-15658 from Fitzgerald
|
||||||||||
AKR7A3 antibody - 70R-4223 from Fitzgerald
|
||||||||||
AKR7A3 Antibody - abx110930 from Abbexa
|