| Gene Symbol |
CCNO
|
| Entrez Gene |
10309
|
| Alt Symbol |
CCNU, CILD29, UDG2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cyclin O
|
| Other Description |
cyclin U|cyclin domain containing|cyclin-O
|
| Swissprots |
Q0P6J2 A8K1W5 Q9H6B0 P22674 Q9UMD5
|
| Accessions |
AAB05817 EAW54912 EAW54913 P22674 AK026075 BAB15351 AK290030 BAF82719 BC004877 AAH04877 BC017345 BC056254 BC143905 BC143907 BC160041 AAI60041 BI832060 BX096363 HY011414 X52486 CAA36728 NM_021147 NP_066970 NR_125346 NR_125347 NR_125348 NM_001024592
|
| Function |
Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation. Acts downstream of MCIDAS to promote mother centriole amplification and maturation in preparation for apical docking. {ECO:0000269|PubMed:24747639}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:24747639}. Note=Localizes to the apical part of cytoplasm. {ECO:0000269|PubMed:24747639}.
|
| Tissue Specificity |
Present in respiratory cells (at protein level). {ECO:0000269|PubMed:24747639}.
|
![Western Blot: Cyclin-O Overexpression Lysate (Adult Normal) [NBP2-06557] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Cyclin-O.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4776_Cyclin-O%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06557-img0001.jpg)