Gene Symbol | DDX19B |
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Entrez Gene | 11269 |
Alt Symbol | DBP5, DDX19, RNAh |
Species | Human |
Gene Type | protein-coding |
Description | DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B |
Other Description | ATP-dependent RNA helicase DDX19|ATP-dependent RNA helicase DDX19B|DEAD (Asp-Glu-Ala-As) box polypeptide 19B|DEAD box RNA helicase DEAD5|DEAD box protein 19B|DEAD-box RNA helicase DEAD5|DEAD-box protein 5|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (Dbp5, yeast, homolog)|yeast Dbp5 homolog |
Swissprots | Q6IAE0 Q6FIB7 Q9H0U0 Q96KE7 E7EMK4 B4DXS6 B3KNE9 Q9UMR2 |
Accessions | EAW51827 EAW51831 EAW51832 EAW51833 EAW51834 EAW51836 EAW51837 Q9UMR2 AF353720 AAK40102 AJ237946 CAB52189 AK027378 BAG51311 AK223115 BAD96835 AK296868 BAG59431 AK301938 BAG63358 AK302107 BAG63488 AK316346 BAH14717 AL136639 CAB66574 BC003626 AAH03626 BC010008 AAH10008 BC110805 AAI10806 BI756088 CR457215 CAG33496 CR533509 CAG38540 DC385044 EU831645 ACE87245 EU831729 ACE86563 HQ448249 ADQ32729 XM_006721127 XP_006721190 XM_011522832 XP_011521134 XM_011522833 XP_011521135 XM_011522834 XP_011521136 NM_001014449 NP_001014449 NM_001014451 NP_001014451 NM_001257172 NP_001244101 NM_001257173 NP_001244102 NM_001257174 NP_001244103 NM_001257175 NP_001244104 NM_007242 NP_009173 |
Function | ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins. |
Subcellular Location | Cytoplasm. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Nuclear pore complex cytoplasmic fibrils. |
Dbp5 CRISPR/Cas9 KO Plasmid (h) - sc-417501 from Santa Cruz Biotechnology
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Dbp5 HDR Plasmid (h) - sc-417501-HDR from Santa Cruz Biotechnology
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Dbp5 Double Nickase Plasmid (h) - sc-417501-NIC from Santa Cruz Biotechnology
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Dbp5 Double Nickase Plasmid (h2) - sc-417501-NIC-2 from Santa Cruz Biotechnology
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Dbp5 CRISPR Activation Plasmid (h) - sc-417501-ACT from Santa Cruz Biotechnology
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Dbp5 CRISPR Activation Plasmid (h2) - sc-417501-ACT-2 from Santa Cruz Biotechnology
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Dbp5 Lentiviral Activation Particles (h) - sc-417501-LAC from Santa Cruz Biotechnology
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Dbp5 Lentiviral Activation Particles (h2) - sc-417501-LAC-2 from Santa Cruz Biotechnology
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DDX19B siRNA (h) - sc-77097 from Santa Cruz Biotechnology
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DDX19B shRNA Plasmid (h) - sc-77097-SH from Santa Cruz Biotechnology
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DDX19B shRNA (h) Lentiviral Particles - sc-77097-V from Santa Cruz Biotechnology
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DDX19B RNAi - H00011269-R06 from Novus Biologicals
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DDX19B RNAi - H00011269-R04 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN7043 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7043 from Sigma-Aldrich
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DDX19B siRNA (Human) - CRH7725 from Cohesion Biosciences
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DDX19B RNAi - H00011269-R05 from Novus Biologicals
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DDX19B - MBS8218872 from MyBioSource
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DDX19B shRNA Plasmid (Human) - CHH7725 from Cohesion Biosciences
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DDX19B miRNA 3'UTR clone - MiUTR3H-07975 from Creative biogene
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DDX19B miRNA 3'UTR clone - MiUTR3H-07976 from Creative biogene
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DDX19B miRNA 3'UTR clone - MiUTR3H-07977 from Creative biogene
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