| Gene Symbol | ADH7 |
|---|---|
| Entrez Gene | 131 |
| Alt Symbol | ADH4 |
| Species | Human |
| Gene Type | protein-coding |
| Description | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| Other Description | alcohol dehydrogenase VII|alcohol dehydrogenase class 4 mu/sigma chain|alcohol dehydrogenase class IV mu/sigma chain|alcohol dehydrogenase-7|class IV sigma-1 alcohol dehydrogenase|class IV sigmasigma alcohol dehydrogenase|gastric alcohol dehydrogenase|retinol dehydrogenase |
| Swissprots | Q13713 A8MVN9 B4DWV6 B2R760 P40394 A2RRB6 |
| Accessions | AAB38424 AAC51351 EAX06101 P40394 AK223472 AK301657 BAG63133 AK301696 BAG63168 AK310811 AK312854 BAG35707 BC131512 AAI31513 BX476080 CA311897 CD014081 CD697521 DB204496 DB350054 L33179 AAA59211 S77168 AAB34478 U07821 AAA19002 U09623 AAA82165 X76342 CAA53960 NM_000673 NP_000664 NM_001166504 NP_001159976 |
| Function | Could function in retinol oxidation for the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism. |
| Subcellular Location | Cytoplasm. |
| Tissue Specificity | Preferentially expressed in stomach. |
| Top Pathways | Glycolysis / Gluconeogenesis, Chemical carcinogenesis, Tyrosine metabolism, Fatty acid degradation, Retinol metabolism |