Gene Symbol | CAPNS1 |
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Entrez Gene | 826 |
Alt Symbol | CALPAIN4, CANP, CANPS, CAPN4, CDPS, CSS1 |
Species | Human |
Gene Type | protein-coding |
Description | calpain, small subunit 1 |
Other Description | CANP small subunit|calcium-activated neutral proteinase small subunit|calcium-dependent protease small subunit 1|calcium-dependent protease, small subunit|calpain 4, small subunit (30K)|calpain regulatory subunit|calpain small subunit 1|calpain, small polypeptide |
Swissprots | A8K0P1 Q96EW0 P04632 Q8WTX3 |
Accessions | AAA35646 AAB51183 AAB81546 AAV40829 P04632 AK289606 BAF82295 AY007141 BC000592 AAH00592 BC007779 AAH07779 BC011903 AAH11903 BC017308 AAH17308 BC018931 AAH18931 BC021933 AAH21933 BC023643 AAH23643 BC064998 AAH64998 BF822052 BQ891655 BQ898664 BT009775 AAP88777 CN349928 DR759763 HY003903 X04106 CAA27726 XM_005259295 XP_005259352 XM_005259296 XP_005259353 XM_011527359 XP_011525661 NM_001003962 NP_001003962 NM_001302632 NP_001289561 NM_001302633 NP_001289562 NM_001749 NP_001740 |
Function | Regulatory subunit of the calcium-regulated non- lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Translocates to the plasma membrane upon calcium binding. {ECO:0000250}. |
Calpain reg CRISPR/Cas9 KO Plasmid (h) - sc-403478 from Santa Cruz Biotechnology
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Calpain reg HDR Plasmid (h) - sc-403478-HDR from Santa Cruz Biotechnology
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Calpain reg Double Nickase Plasmid (h) - sc-403478-NIC from Santa Cruz Biotechnology
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Calpain reg Double Nickase Plasmid (h2) - sc-403478-NIC-2 from Santa Cruz Biotechnology
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Calpain reg CRISPR Activation Plasmid (h) - sc-403478-ACT from Santa Cruz Biotechnology
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Calpain reg CRISPR Activation Plasmid (h2) - sc-403478-ACT-2 from Santa Cruz Biotechnology
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Calpain reg Lentiviral Activation Particles (h) - sc-403478-LAC from Santa Cruz Biotechnology
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Calpain reg Lentiviral Activation Particles (h2) - sc-403478-LAC-2 from Santa Cruz Biotechnology
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Calpain reg siRNA (h) - sc-29887 from Santa Cruz Biotechnology
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Calpain reg shRNA Plasmid (h) - sc-29887-SH from Santa Cruz Biotechnology
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Calpain reg shRNA (h) Lentiviral Particles - sc-29887-V from Santa Cruz Biotechnology
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Calpain small subunit 1 RNAi - H00000826-R01V from Novus Biologicals
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MISSION® esiRNA - EHU047191 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5350 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5350 from Sigma-Aldrich
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CAPNS1 siRNA (Human) - CRH0580 from Cohesion Biosciences
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Calpain small subunit 1 RNAi - H00000826-R01 from Novus Biologicals
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Calpain small subunit 1 RNAi - H00000826-R02 from Novus Biologicals
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CAPNS1 - MBS8231441 from MyBioSource
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Calpain reg CRISPR/Cas9 KO Plasmid (h2) - sc-403478-KO-2 from Santa Cruz Biotechnology
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Calpain reg HDR Plasmid (h2) - sc-403478-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human CAPNS1 (NM_001749.2) - SHH254417 from Creative biogene
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shRNA set against Human CAPNS1(NM_001003962.1) - SHG140281 from Creative biogene
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CAPNS1 shRNA Plasmid (Human) - CHH0580 from Cohesion Biosciences
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CAPNS1 miRNA 3'UTR clone - MiUTR1H-01660 from Creative biogene
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