| Gene Symbol | DAO1 |
|---|---|
| Entrez Gene | 397134 |
| Alt Symbol | DAAO, DAMOX, DAO |
| Species | Pig |
| Gene Type | protein-coding |
| Description | D-amino acid oxidase |
| Other Description | D-amino-acid oxidase |
| Swissprots | P00371 |
| Accessions | P00371 AK233002 M16972 AAA30985 M18448 AAA31026 NM_214066 NP_999231 |
| Function | Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. |
| Subcellular Location | Peroxisome. |
| Top Pathways | Glycine, serine and threonine metabolism, Peroxisome, Arginine and proline metabolism, D-Arginine and D-ornithine metabolism |