MYDGF

Gene Symbol MYDGF
Entrez Gene 56005
Alt Symbol C19orf10, EUROIMAGE1875335, IL25, IL27, IL27w, R33729_1, SF20
Species Human
Gene Type protein-coding
Description myeloid-derived growth factor
Other Description UPF0556 protein C19orf10|interleukin 25|interleukin 27 working designation|interleukin-25|stromal cell-derived growth factor SF20
Swissprots Q9NP69 O75256 Q969H8 O75272 Q9BTK7 D6W628
Accessions AAC27824 AAC33800 EAW69202 EAW69203 Q969H8 AF282264 AK098829 AL365373 CAB96947 AL365374 CAB96948 BC003639 AAH03639 BC010129 AAH10129 BC014655 AAH14655 BG484758 NM_019107 NP_061980
Function Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway (By similarity). Involved in endothelial cell proliferation and angiogenesis (PubMed:25581518). {ECO:0000250|UniProtKB:Q9CPT4, ECO:0000269|PubMed:25581518}.
Subcellular Location Secreted {ECO:0000269|PubMed:17362502, ECO:0000269|PubMed:25581518}. Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000269|PubMed:17362502}. Note=Secreted into blood plasma. {ECO:0000269|PubMed:25581518}.
Tissue Specificity Expressed in bone marrow cells (PubMed:25581518). Expressed in synovial tissue. Found in synovial fluid of patients with arthropaties (PubMed:17362502). {ECO:0000269|PubMed:17362502, ECO:0000269|PubMed:25581518}.

IL-25 CRISPR/Cas9 KO Plasmid (h) - sc-404776 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-25 HDR Plasmid (h) - sc-404776-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-25 Double Nickase Plasmid (h) - sc-404776-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-25 Double Nickase Plasmid (h2) - sc-404776-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-25 CRISPR Activation Plasmid (h) - sc-404776-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-25 CRISPR Activation Plasmid (h2) - sc-404776-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-25 Lentiviral Activation Particles (h) - sc-404776-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-25 Lentiviral Activation Particles (h2) - sc-404776-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-25 siRNA (h) - sc-105567 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-25 shRNA Plasmid (h) - sc-105567-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-25 shRNA (h) Lentiviral Particles - sc-105567-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL25 RNAi - H00056005-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

IL-27 RNAi - H00246778-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU045981 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4517 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4517 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03394 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03394

C19orf10 siRNA (Human) - CRJ1039 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

C19orf10 - MBS8208736 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human C19orf10 (NM_019107.3) - SHH250082 from Creative biogene

Category siRNA
Species Reactivities Human

Human C19orf10 siRNA - orb271540 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

C19orf10 shRNA Plasmid (Human) - CHJ1039 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

C19ORF10 miRNA 3'UTR clone - MiUTR1H-01192 from Creative biogene

Species Reactivities Human
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