Gene Symbol | IL6 |
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Entrez Gene | 280826 |
Alt Symbol | - |
Species | Bovine |
Gene Type | protein-coding |
Description | interleukin 6 |
Other Description | IL-6|interleukin 6 (interferon, beta 2)|interleukin-6 |
Swissprots | P26892 Q08DT2 A9QWQ9 |
Accessions | DAA30705 P26892 BC123577 AAI23578 EU276071 ABX72069 X57317 CAA40572 NM_173923 NP_776348 |
Function | Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig- secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted. |
Top Pathways | Legionellosis, Herpes simplex infection, TNF signaling pathway, Non-alcoholic fatty liver disease (NAFLD), PI3K-Akt signaling pathway |
Recombinant Bovine Interleukin 6 (Interferon, Beta 2) - IL6-241B from Creative Biomart
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IL6 - PKF-1002 from Nordic BioSite
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Recombinant Bovine Interleukin-6(IL6) - CSB-YP011664BO CSB-EP011664BO CSB-BP011664BO CSB-MP011664BO from Cusabio
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Bovine IL-6 Recombinant Protein - 6371 from ImmunoChemistry Technologies
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IL-6 - PBP021 from AbD Serotec
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Interleukin-6 (IL6), Recombinant Protein - MBS717913 from MyBioSource
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