RCC1

Gene Symbol RCC1
Entrez Gene 1104
Alt Symbol CHC1, RCC1-I, SNHG3-RCC1
Species Human
Gene Type protein-coding
Description regulator of chromosome condensation 1
Other Description SNHG3-RCC1 readthrough|cell cycle regulatory protein|guanine nucleotide-releasing protein|regulator of chromosome condensation
Swissprots Q6NT97 Q16269 P18754
Accessions BAA00469 EAX07690 EAX07691 EAX07692 EAX07693 EAX07694 EAX07695 P18754 AF498924 AAM21072 AI198971 BC001589 BC010067 AAH10067 BC069198 AAH69198 BF590413 BF667678 BM546148 BQ436549 BU501614 BU622451 BX109495 CB985055 CR407693 CAG28621 CV811053 DQ893153 ABM84079 DQ896760 ABM87759 S75708 AAB32653 X12654 CAA31182 NM_001048194 NP_001041659 NM_001048195 NP_001041660 NM_001048199 NP_001041664 NM_001269 NP_001260 NR_030725 NR_030726
Function Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo- cytoplasmic transport, mitosis and nuclear-envelope assembly. {ECO:0000269|PubMed:1944575}.
Subcellular Location Nucleus {ECO:0000269|PubMed:17435751}. Cytoplasm {ECO:0000269|PubMed:17435751}. Note=Becomes dispersed throughout the cytoplasm during mitosis.

Phospho-RCC1 (Ser11) Antibody - 4210 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HT-29 cells, untreated or synchronized in mitosis by thymidine block and released into nocodazole, using Phospho-RCC1 (Ser11) Antibody (upper) or RCC1 Antibody #3589 (lower).

Phospho-RCC1 (Ser11) (D18B5) Rabbit mAb - 5500 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D18B5
Western blot analysis of extracts from HeLa cells, untreated (-) or synchronized in mitosis by thymidine block and released into nocodazole (+), using Phospho-RCC1 (Ser11) (D18B5) Rabbit mAb (upper) or RCC1 (D15H6) Rabbit mAb #5134 (lower).

RCC1 Antibody - 3589 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell types using RCC1 Antibody.

RCC1 (D15H6) Rabbit mAb - 5134 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D15H6
Western blot analysis of extracts from various cell types using RCC1 (D15H6) Rabbit mAb.

RCC1 (C-6) - sc-374325 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RCC1 (C-6): sc-374325. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear and cytoplasmic localization.

RCC1 (H-300) - sc-25635 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
RCC1 (H-300): sc-25635. Western blot analysis of RCC1 expression in non-transfected: sc-117752 (A) and mouse RCC1 transfected: sc-125894 (B) 293T whole cell lysates.

RCC1 (F-2) - sc-376049 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RCC1 (F-2): sc-376049. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.

RCC1 (H-5) - sc-376715 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RCC1 (H-5): sc-376715. Western blot analysis of RCC1 expression in Jurkat whole cell lysate (A) and A-431 nuclear extract (B).

RCC1 (E-6) - sc-55559 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RCC1 (E-6): sc-55559. Western blot analysis of RCC1 expression in A-431 (A) and NIH/3T3 (B) nuclear extracts.

RCC1 (N-19) - sc-1161 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RCC1 (N-19): sc-1161. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human colon carcinoma tissue showing nuclear localization.

RCC1 (C-20) - sc-1162 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RCC1 (C-20): sc-1162. Immunofluorescence staining of formalin-fixed HeLa cells showing nuclear localization. Kindly provided by Yang Xiang, Ph.D., Division of Newborn Medicine, Boston Childrens Hospital, Cell Biology Department, Harvard Medical School.

RCC1 (9) - sc-136056 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/500 µl
Host Mouse
Clonality Monoclonal
RCC1 (9): sc-136056. Western blot analysis of RCC1 expression in human endothelial whole cell lysate.

Anti-RCC1 antibody - ab54600 from Abcam

Prices $388.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
RCC1 antibody (ab54600) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human thyroid nodular goiter.

Anti-RCC1 antibody - ab152156 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of paraformaldehyde-fixed A431 cells, staining RCC1 (green) using ab152156 at a 1/200 dilution.

Anti-RCC1 antibody - ab4785 from Abcam

Prices $378.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
ab4785 (1/100) staining RCC1 in Skin tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).

Anti-RCC1 antibody - ab88798 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-RCC1 antibody (ab88798) at 1 µg/ml + human colon tissue lysate at 50 µg

Anti-RCC1 antibody - ab70749 from Abcam

Prices $376.00
Sizes 100 µl
Host Goat
Clonality Polyclonal
All lanes : Anti-RCC1 antibody (ab70749) at 1/2000 dilutionLane 1 : Human RCC1 full length protein (ab90625) at 0.01 µgLane 2 : Human RCC1 full length protein (ab90625) at 0.1 µgSecondaryRabbit polyclonal to Goat IgG - H&L - Pre-Adsorbed (HRP) (ab65486) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.Exposure time : 8 minutes

Anti-RCC1 antibody - ab36760 from Abcam

Prices $376.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
Ab36760 staining human RCC1 in human colon carcinoma by immunohistochemistry using formalin fixed, paraffin embedded tissue.

Anti-RCC1 antibody - ab53719 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RCC1 antibody (ab53719) at 1/500 dilutionLane 1 : Extracts from LoVo cells, minus immunising peptideLane 2 : Extracts from LoVo cells, plus immunising peptide

Anti-RCC1 antibody [2F1] - ab124391 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2F1
Anti-RCC1 antibody [2F1] (ab124391) at 1/500 dilution + A431 cell lysate

Anti-RCC1 antibody [EPR5857] - ab109379 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5857
All lanes : Anti-RCC1 antibody [EPR5857] (ab109379) at 1/1000 dilutionLane 1 : A431 cell lysateLane 2 : HeLa cell lysateLane 3 : Jurkat cell lysateLane 4 : 293T cell lysateLysates/proteins at 10 µg per lane.

Anti-RCC1 antibody [EPR5859(2)] - ab181155 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5859(2)
Western Blot analysis of RCC1 in HeLa cell lysate immunoprecipitated with ab181155 at 1/50 dilution (Lane 1). Lane 2: Negative control.Secondary: Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1500 dilution.

Anti-RCC1 antibody - Aminoterminal end, prediluted - ab53650 from Abcam

Prices $376.00
Sizes 7 ml
Host Rabbit
Clonality Polyclonal
ab53650, used neat, staining Human RCC1 in Colon carcinoma, using Immunohistochemistry, Formalin fixed Paraffin embedded tissue

Anti-RCC1 Antibody (phospho-Ser11) - LS-C131814 from LifeSpan Bioscience

Prices $355.00
Sizes 40 µl
Host Rabbit
Clonality Polyclonal

Anti-RCC1 Antibody - LS-C82249 from LifeSpan Bioscience

Prices $380.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of RanGEF (RCC1) on formalin fixed paraffin embedded skin tissue at 1:100
Search more