Gene Symbol | RCC1 |
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Entrez Gene | 1104 |
Alt Symbol | CHC1, RCC1-I, SNHG3-RCC1 |
Species | Human |
Gene Type | protein-coding |
Description | regulator of chromosome condensation 1 |
Other Description | SNHG3-RCC1 readthrough|cell cycle regulatory protein|guanine nucleotide-releasing protein|regulator of chromosome condensation |
Swissprots | Q6NT97 Q16269 P18754 |
Accessions | BAA00469 EAX07690 EAX07691 EAX07692 EAX07693 EAX07694 EAX07695 P18754 AF498924 AAM21072 AI198971 BC001589 BC010067 AAH10067 BC069198 AAH69198 BF590413 BF667678 BM546148 BQ436549 BU501614 BU622451 BX109495 CB985055 CR407693 CAG28621 CV811053 DQ893153 ABM84079 DQ896760 ABM87759 S75708 AAB32653 X12654 CAA31182 NM_001048194 NP_001041659 NM_001048195 NP_001041660 NM_001048199 NP_001041664 NM_001269 NP_001260 NR_030725 NR_030726 |
Function | Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo- cytoplasmic transport, mitosis and nuclear-envelope assembly. {ECO:0000269|PubMed:1944575}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:17435751}. Cytoplasm {ECO:0000269|PubMed:17435751}. Note=Becomes dispersed throughout the cytoplasm during mitosis. |
Human RCC1 full length protein - ab90625 from Abcam
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RCC1 Antibody Blocking Peptide - LS-E22423 from LifeSpan Bioscience
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RCC1 Antibody Blocking Peptide - LS-E22422 from LifeSpan Bioscience
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Recombinant Human RCC1 Protein - H00001104-P01 from Novus Biologicals
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Recombinant Human RCC1 Protein - H00001104-Q01 from Novus Biologicals
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RCC1 Peptide - P0671 from Novus Biologicals
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RCC1 Peptide - P0670 from Novus Biologicals
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RCC1-Antibody-C-term-Blocking-Peptide - BP1919b from Abgent, a WuXi AppTec company
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RCC1-Antibody-N-term-Blocking-Peptide - BP1919a from Abgent, a WuXi AppTec company
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RCC1 Blocking Peptide - 33R-1623 from Fitzgerald
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RCC1 / CHC1 - H00001104-P01-10 from Acris Antibodies
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RCC1 / CHC1 - H00001104-P01-25 from Acris Antibodies
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RCC1 / CHC1 - H00001104-Q01-10 from Acris Antibodies
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RCC1 / CHC1 - H00001104-Q01-25 from Acris Antibodies
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RCC1 fusion protein - Ag17809 from Proteintech Group
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RCC1 fusion protein - ag17698 from Proteintech Group
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RCC1 fusion protein - ag17569 from Proteintech Group
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RCC1 fusion protein - ag17826 from Proteintech Group
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SNHG3-RCC1 fusion protein - ag1042 from Proteintech Group
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Recombinant Human Regulator Of Chromosome Condensation 1 - RCC1-1139H from Creative Biomart
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Recombinant Human RCC1, GST-tagged - RCC1-2229H from Creative Biomart
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Native Human RCC1 - RCC1-31302TH from Creative Biomart
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Recombinant Human Regulator of chromosome condensation(RCC1) - CSB-YP019505HU CSB-EP019505HU CSB-BP019505HU CSB-MP019505HU from Cusabio
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SNHG3-RCC1 fusion protein - Ag24891 from Proteintech Group
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RCC1 / CHC1 (transcript variant 3) - TP303556 from Acris Antibodies
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