| Gene Symbol | MAOA |
|---|---|
| Entrez Gene | 4128 |
| Alt Symbol | MAO-A |
| Species | Human |
| Gene Type | protein-coding |
| Description | monoamine oxidase A |
| Other Description | amine oxidase [flavin-containing] A|monoamine oxidase type A |
| Swissprots | P21397 Q16426 B4DF46 |
| Accessions | AAA59547 AAB46385 AAD14113 AAD14361 AAV34705 AAV34711 AAV34717 AAV34720 BAA95955 EAW59381 EAW59382 EAW59383 P21397 AK223499 BAD97219 AK291769 BAF84458 AK293926 BAG57307 BC008064 AAH08064 BC044787 AAH44787 BG534382 BT006651 AAP35297 BU684121 BX501303 DQ890676 ABM81602 DQ893857 ABM84783 M68840 AAA59548 M69226 AAA59549 X17192 NM_000240 NP_000231 NM_001270458 NP_001257387 |
| Function | Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine. |
| Subcellular Location | Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side. |
| Tissue Specificity | Heart, liver, duodenum, blood vessels and kidney. |
| Top Pathways | Glycine, serine and threonine metabolism, Dopaminergic synapse, Amphetamine addiction, Cocaine addiction, Alcoholism |