| Gene Symbol |
ATP6V1D
|
| Entrez Gene |
51382
|
| Alt Symbol |
ATP6M, VATD, VMA8
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
| Other Description |
ATPase, H+ transporting lysosomal, member M|ATPase, H+ transporting, lysosomal (vacuolar proton pump)|H(+)-transporting two-sector ATPase, subunit M|V-ATPase 28 kDa accessory protein|V-ATPase D subunit|V-ATPase subunit D|V-type proton ATPase subunit D|vacuolar ATP synthase subunit D|vacuolar H-ATPase subunit D|vacuolar proton pump D subunit|vacuolar proton pump delta polypeptide|vacuolar proton pump subunit D|vacuolar proton-ATPase subunit D
|
| Swissprots |
Q9Y688 B2RE33 Q9Y5K8
|
| Accessions |
EAW80931 EAW80932 Q9Y5K8 AF077614 AAG43047 AF100741 AAD40384 AF104629 AAG30726 AF145316 AAD33953 AK001155 BAA91523 AK315784 BAG38130 BC001411 AAH01411 BC025373 AAH25373 BC031002 AAH31002 BF669634 BG236185 BU726615 DB039102 HQ447570 ADQ32056 NM_015994 NP_057078
|
| Function |
Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity). May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium. {ECO:0000250, ECO:0000269|PubMed:21844891}.
|
| Subcellular Location |
Membrane {ECO:0000305|PubMed:21844891}; Peripheral membrane protein {ECO:0000305|PubMed:21844891}; Cytoplasmic side {ECO:0000305|PubMed:21844891}. Note=Localizes to centrosome and the base of the cilium.
|
| Top Pathways |
Epithelial cell signaling in Helicobacter pylori infection, Vibrio cholerae infection, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis
|