FRZB

Gene Symbol FRZB
Entrez Gene 2487
Alt Symbol FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, OS1, SFRP3, SRFP3, hFIZ
Species Human
Gene Type protein-coding
Description frizzled-related protein
Other Description frezzled|frizzled homolog-related|frizzled-related protein 1|sFRP-3|secreted frizzled-related protein 3
Swissprots Q92765 O00181 Q99686
Accessions AAX93117 AAY24241 ADL14515 EAX10958 Q92765 AK130009 AK312741 BAG35611 AU117730 BC027855 AAH27855 BE549700 BF058813 BT019883 AAV38686 DQ890944 ABM81870 DQ894106 ABM85032 U24163 AAC50736 U68057 AAC51217 U91903 AAB51298 NM_001463 NP_001454
Function Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.
Subcellular Location Secreted {ECO:0000305}.
Tissue Specificity Expressed primarily in the cartilaginous cores of the long bone during embryonic and fetal development and in the appendicular skeleton (6-13 weeks). At 13 weeks of gestation, transcripts were present in early chondroblasts of the tarsal bones of the foot, the carpal bones of the hands and the epiphysis of long bones. Highly expressed in placenta and heart, followed by brain, skeletal muscle, kidney and pancreas. Weakly expressed in lung and liver.

FRP-3 CRISPR/Cas9 KO Plasmid (h) - sc-402504 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FRP-3 HDR Plasmid (h) - sc-402504-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FRP-3 Double Nickase Plasmid (h) - sc-402504-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FRP-3 Double Nickase Plasmid (h2) - sc-402504-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FRP-3 CRISPR Activation Plasmid (h) - sc-402504-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FRP-3 CRISPR Activation Plasmid (h2) - sc-402504-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FRP-3 Lentiviral Activation Particles (h) - sc-402504-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FRP-3 Lentiviral Activation Particles (h2) - sc-402504-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FRP-3 siRNA (h) - sc-35411 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FRP-3 shRNA Plasmid (h) - sc-35411-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FRP-3 shRNA (h) Lentiviral Particles - sc-35411-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

sFRP-3/FRZB RNAi - H00002487-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU050261 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8959 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8959 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07188 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07188

FRZB siRNA (Human) - CRH1655 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FRZB - MBS8231159 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FRZB (NM_001463.3) - SHH297289 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human FRZB(NM_001463.3) - SHH068697 from Creative biogene

Category siRNA
Species Reactivities Human

Human FRZB siRNA - orb262157 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FRZB shRNA Plasmid (Human) - CHH1655 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FRZB miRNA 3'UTR clone - MiUTR1H-03858 from Creative biogene

Species Reactivities Human
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