GADD45A

Gene Symbol	GADD45A
Entrez Gene	1647
Alt Symbol	DDIT1, GADD45
Species	Human
Gene Type	protein-coding
Description	growth arrest and DNA-damage-inducible, alpha
Other Description	DDIT-1|DNA damage-inducible transcript 1 protein|DNA damage-inducible transcript-1|DNA-damage-inducible transcript 1|growth arrest and DNA damage-inducible protein GADD45 alpha|growth arrest and DNA-damage-inducible 45 alpha
Swissprots	Q5TCA8 Q5TCA7 P24522
Accessions	AAA72045 AAM88884 CBX53896 EAX06487 EAX06488 P24522 AK314991 BAG37487 AM393439 CAL38317 BC011757 AAH11757 BU629410 DQ008445 AAY25021 DQ893229 ABM84155 DQ896558 ABM87557 EF581092 ABQ52427 EF614238 M60974 AAA35863 NM_001199741 NP_001186670 NM_001199742 NP_001186671 NM_001924 NP_001915
Function	In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:7973727}.
Top Pathways	Cell cycle, p53 signaling pathway, MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GADD 45α CRISPR/Cas9 KO Plasmid (h) - sc-418216 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

GADD 45α HDR Plasmid (h) - sc-418216-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GADD 45α Double Nickase Plasmid (h) - sc-418216-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GADD 45α Double Nickase Plasmid (h2) - sc-418216-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GADD 45α CRISPR Activation Plasmid (h) - sc-418216-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

GADD 45α CRISPR Activation Plasmid (h2) - sc-418216-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

GADD 45α Lentiviral Activation Particles (h) - sc-418216-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GADD 45α Lentiviral Activation Particles (h2) - sc-418216-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

GADD 45α siRNA (h) - sc-35440 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

GADD 45α shRNA Plasmid (h) - sc-35440-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

GADD 45α shRNA (h) Lentiviral Particles - sc-35440-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

GADD45 alpha RNAi - H00001647-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU051621 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1441 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit - CKOZFN1440 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit - CKOZFN1439 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1440 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1439 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1441 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04364 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr04364

GADD45A siRNA (Human) - CRH1161 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

GADD45A - MBS8233375 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

GADD45A shRNA Plasmid (Human) - CHH1161 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

GADD45A miRNA 3'UTR clone - MiUTR3H-00675 from Creative biogene Species Reactivities Human

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