Gene Symbol | SLC36A1 |
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Entrez Gene | 206358 |
Alt Symbol | Dct1, LYAAT1, PAT1, TRAMD3 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 36 (proton/amino acid symporter), member 1 |
Other Description | hPAT1|lysosomal amino acid transporter 1|proton-coupled amino acid transporter 1|proton/amino acid transporter 1|solute carrier family 36 member 1 |
Swissprots | Q96M74 Q86YK4 Q7Z7C0 Q1LZ56 C9JI34 Q7Z2H8 |
Accessions | EAW61674 EAW61675 EAW61676 EAW61677 Q7Z2H8 AF516142 AAP47194 AK000729 AK025102 AK057340 BAB71435 AK309323 AL833703 AM393725 CAL38601 AY162213 AAO11787 AY227111 AAO37091 AY227112 AAO37092 AY227113 AAO37093 BC136437 AAI36438 BC136438 AAI36439 BC146685 AAI46686 BF439390 BK001052 DAA01126 BM787446 BX537963 CAD97927 EU832292 ACE87549 EU832376 ACE86861 GU296670 ADB56966 XM_005268386 XP_005268443 XM_006714759 XP_006714822 XM_011537580 XP_011535882 XM_011537581 XP_011535883 XM_011537582 XP_011535884 XM_011537583 XP_011535885 XM_011537584 XP_011535886 XM_011537585 XP_011535887 XM_011537586 XP_011535888 XM_011537587 XP_011535889 XM_011537588 XP_011535890 XM_011537589 XP_011535891 XM_011537590 XP_011535892 XM_011537591 XP_011535893 XM_011537592 XP_011535894 XM_011537593 XP_011535895 XM_011537594 XP_011535896 XM_011537595 XP_011535897 XM_011537596 XP_011535898 XM_011537597 XP_011535899 XR_944309 NM_001308150 NP_001295079 NM_001308151 NP_001295080 NM_078483 NP_510968 |
Function | Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Besides small apolar L-amino acids, it also recognize their D-enantiomers and selected amino acid derivatives such as gamma-aminobutyric acid (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Lysosome membrane {ECO:0000269|PubMed:17897319}; Multi-pass membrane protein {ECO:0000269|PubMed:17897319}. |
Top Pathways | Protein digestion and absorption |
PAT1 (D-13) - sc-161148 from Santa Cruz Biotechnology
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PAT1 (G-13) - sc-161149 from Santa Cruz Biotechnology
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PAT1 (H-56) - sc-368553 from Santa Cruz Biotechnology
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PAT1 (N-13) - sc-161150 from Santa Cruz Biotechnology
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Anti-SLC36A1 antibody - ab110513 from Abcam
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Anti-SLC36A1 antibody - N-terminal - ab189441 from Abcam
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Anti-SLC36A1 Antibody (aa1-30, APC) - LS-C240922 from LifeSpan Bioscience
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Anti-SLC36A1 Antibody (aa1-30, AP) - LS-C240925 from LifeSpan Bioscience
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Anti-SLC36A1 Antibody (aa1-30, PE) - LS-C240929 from LifeSpan Bioscience
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Anti-SLC36A1 Antibody (aa1-30, FITC) - LS-C240924 from LifeSpan Bioscience
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Anti-SLC36A1 Antibody (aa1-30, Biotin) - LS-C240926 from LifeSpan Bioscience
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Anti-SLC36A1 Antibody (aa1-30, Azide-free, HRP) - LS-C248186 from LifeSpan Bioscience
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Anti-SLC36A1 Antibody (aa1-30) - LS-C325165 from LifeSpan Bioscience
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Anti-SLC36A1 Antibody (N-Terminus) - LS-C151676 from LifeSpan Bioscience
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Anti-SLC36A1 Antibody (aa1-30) IHC-plus⢠- LS-B9339 from LifeSpan Bioscience
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SLC36A1 Antibody - NBP2-30037 from Novus Biologicals
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SLC36A1 Antibody - NBP1-81280 from Novus Biologicals
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Anti-SLC36A1 antibody produced in rabbit - SAB2107834 from Sigma-Aldrich
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ANTI-SLC36A1 (N-TERM) antibody produced in rabbit - SAB1302843 from Sigma-Aldrich
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Anti-SLC36A1 antibody produced in rabbit - HPA035937 from Sigma-Aldrich
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SLC36A1 antibody - N-terminal region (ARP64286_P050) - ARP64286_P050 from Aviva Systems Biology
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SLC36A1-Antibody-N-term - AP12170a from Abgent, a WuXi AppTec company
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SLC36A1 Antibody - N-terminal region (OAAB08411) - OAAB08411 from Aviva Systems Biology
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SLC36A1 antibody - orb178789 from Biorbyt
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SLC36A1 Antibody - abx026632 from Abbexa
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