DSCAM

Gene Symbol DSCAM
Entrez Gene 1826
Alt Symbol CHD2, CHD2-42, CHD2-52
Species Human
Gene Type protein-coding
Description Down syndrome cell adhesion molecule
Other Description -
Swissprots O60469 O60468
Accessions CAB90436 CAB90444 CAB90464 EAX09620 EAX09621 O60469 AB209136 BAD92373 AF023449 AAC17966 AF023450 AAC17967 AF086100 AF217525 AAF27525 AF289030 AAL56711 BE503065 XM_011529480 XP_011527782 XM_011529481 XP_011527783 NM_001271534 NP_001258463 NM_001389 NP_001380 NR_073202
Function Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self-avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies. Receptor for netrin required for axon guidance independently of and in collaboration with the receptor DCC. In spinal chord development plays a role in guiding commissural axons projection and pathfinding across the ventral midline to reach the floor plate upon ligand binding. Enhances netrin-induced phosphorylation of PAK1 and FYN. Mediates intracellular signaling by stimulating the activation of MAPK8 and MAP kinase p38. {ECO:0000269|PubMed:10925149, ECO:0000269|PubMed:15169762, ECO:0000269|PubMed:18585357, ECO:0000269|PubMed:19196994}.
Subcellular Location Isoform Long: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Note=Localized in the soma, cell membrane, axon and growth cone of dissociated commissural axons. {ECO:0000250}.
Tissue Specificity Primarily expressed in brain.

DSCAM (N-16) - sc-79437 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
DSCAM (N-16): sc-79437. Western blot analysis of DSCAM expression in T98G whole cell lysate (A) and mouse cerebellum tissue extract (B).

DSCAM (W-20) - sc-79438 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
DSCAM (W-20): sc-79438. Western blot analysis of DSCAM expression in T98G whole cell lysate.

Anti-Dscam antibody - ab51974 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-Dscam antibody (ab51974) at 1 µg/ml + NIH/3T3 cell lysate in RIPA buffer at 35 µgObserved band size : 200 kDa (why is the actual band size different from the predicted?)

Anti-Dscam antibody - ab85362 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Dscam antibody (ab85362) at 1 µg/ml + 10 µg HepG2 cell lysateSecondaryHRP conjugated anti-Rabbit IgG diluted 1/50,000.

Anti-Dscam antibody [MM0718-42L19] - ab201600 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0718-42L19

Anti-DSCAM Antibody - LS-C36211 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-DSCAM Antibody (aa18-1595) - LS-C36212 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-DSCAM Antibody - LS-C123421 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-DSCAM Antibody (aa938-952) - LS-C54738 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (1 ug/ml) staining of NIH/3T3 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-DSCAM Antibody (aa1548-1597) IHC-plus™ - LS-B5787 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-DSCAM antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5787 concentration 5 ug/ml.

DSCAM Antibody [Unconjugated] - Long Isoform - AF3666 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Western blot shows 25 ng of Recombinant Human DSCAM (Catalog # 3666-DS) and Recombinant Human DSCAM‑L1 (Catalog # 3315-DL). PVDF Membrane was probed with 0.1 µg/mL of Goat Anti-Human DSCAM Long Isoform Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3666) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). A specific band was detected for DSCAM at approximately 250 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 3.

DSCAM Antibody (399212) [Unconjugated] - Long Isoform - MAB36661 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 399212
Western blot shows 25 ng of Recombinant Human DSCAM (Catalog # 3666-DS) and Recombinant Human DSCAM‑L1 (Catalog # 3315-DL). PVDF Membrane was probed with 1 µg/mL of Mouse Anti-Human DSCAM Long Isoform Monoclonal Antibody (Catalog # MAB36661) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for DSCAM at approximately 250 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 3.

DSCAM Antibody (399204) [Unconjugated] - Long Isoform - MAB3666 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 399204
Western blot shows 25 ng of Recombinant Human DSCAM (Catalog # 3666-DS) and Recombinant Human DSCAM‑L1 (Catalog # 3315-DL). PVDF Membrane was probed with 1 µg/mL of Mouse Anti-Human DSCAM Long Isoform Monoclonal Antibody (Catalog # MAB3666) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for DSCAM at approximately 250 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 3.

DSCAM Antibody - NBP1-59208 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DSCAM Antibody [NBP1-59208] - Amount and Sample Type : 10 cm sq plate myc-DSCAM transfected mouse neuro2a cells Primary Antibody : DSCAM Primary Antibody Dilution : 1:1000 Secondary Antibody : Anti-Rabbit HRP Secondary Antibody Dilution : 1:5000 Gene Name : DSCAM

DSCAM Antibody - NBP2-30716 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: DSCAM Antibody [NBP2-30716] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.

DSCAM Antibody - NB100-41390 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

DSCAM Antibody - H00001826-A01 from Novus Biologicals

Host Mouse
Clonality Polyclonal

Dscam Polyclonal Antibody - bs-11456R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Paraformaldehyde-fixed, paraffin embedded Mouse brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with Dscam Polyclonal Antibody, Unconjugated (bs-11456R) at 1:400 overnight at 4°C, followed by operating according to and DAB staining.

Dscam Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11456R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Dscam Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11456R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Dscam Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11456R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Dscam Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11456R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Dscam Polyclonal Antibody, Cy3 Conjugated - bs-11456R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Dscam Polyclonal Antibody, Cy5 Conjugated - bs-11456R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Dscam Polyclonal Antibody, Cy5.5 Conjugated - bs-11456R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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