Gene Symbol | ACP6 |
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Entrez Gene | 51205 |
Alt Symbol | ACPL1, LPAP, PACPL1 |
Species | Human |
Gene Type | protein-coding |
Description | acid phosphatase 6, lysophosphatidic |
Other Description | acid phosphatase like 1|acid phosphatase-like protein 1|lysophosphatidic acid phosphatase 6|lysophosphatidic acid phosphatase type 6 |
Swissprots | Q9UIG6 Q5T490 Q7LG81 Q6IAQ3 Q59G61 Q9NPH0 |
Accessions | CAI15199 EAW50931 Q9NPH0 AB030039 BAA94309 AB031478 BAA89311 AB209248 BAD92485 AK000657 BAA91310 AK308593 AK310693 AL520992 AY358552 AAQ88916 BC009965 AAH09965 BC011644 BC034686 AAH34686 CR457101 CAG33382 HQ447913 ADQ32397 KJ534759 AHW56399 KJ535036 AHW56675 KJ535044 AHW56683 KJ535055 AHW56694 XM_011509601 XP_011507903 XR_921820 NM_016361 NP_057445 |
Function | Hydrolyzes lysophosphatidic acid (LPA) containing a medium length fatty acid chain to the corresponding monoacylglycerol. Has highest activity with lysophosphatidic acid containing myristate (C14:0), monounsaturated oleate (C18:1) or palmitate (C16:0), and lower activity with C18:0 and C6:0 lysophosphatidic acid. {ECO:0000269|PubMed:10506173, ECO:0000269|PubMed:23807634}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:10506173}. |
Tissue Specificity | Highly expressed in kidney, heart, small intestine, muscle, liver, prostate, testis, ovary and weakly expressed in thymus and colon. {ECO:0000269|PubMed:10506173, ECO:0000269|PubMed:12010880}. |
Top Pathways | Riboflavin metabolism |
ACP6 CRISPR/Cas9 KO Plasmid (h) - sc-408611 from Santa Cruz Biotechnology
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ACP6 HDR Plasmid (h) - sc-408611-HDR from Santa Cruz Biotechnology
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ACP6 Double Nickase Plasmid (h) - sc-408611-NIC from Santa Cruz Biotechnology
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ACP6 Double Nickase Plasmid (h2) - sc-408611-NIC-2 from Santa Cruz Biotechnology
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ACP6 CRISPR Activation Plasmid (h) - sc-408611-ACT from Santa Cruz Biotechnology
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ACP6 CRISPR Activation Plasmid (h2) - sc-408611-ACT-2 from Santa Cruz Biotechnology
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ACP6 Lentiviral Activation Particles (h) - sc-408611-LAC from Santa Cruz Biotechnology
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ACP6 Lentiviral Activation Particles (h2) - sc-408611-LAC-2 from Santa Cruz Biotechnology
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ACP6 siRNA (h) - sc-78582 from Santa Cruz Biotechnology
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ACP6 shRNA Plasmid (h) - sc-78582-SH from Santa Cruz Biotechnology
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ACP6 shRNA (h) Lentiviral Particles - sc-78582-V from Santa Cruz Biotechnology
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ACP6 RNAi - H00051205-R01 from Novus Biologicals
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MISSION® esiRNA - EHU026551 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0010 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0012 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0011 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2740 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2740 from Sigma-Aldrich
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ACP6 siRNA (Human) - CRH9606 from Cohesion Biosciences
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ACP6 - MBS8236919 from MyBioSource
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shRNA set against Human ACP6 (NM_016361.3) - SHH230586 from Creative biogene
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shRNA set against Human ACP6(NM_016361.3) - SHG031193 from Creative biogene
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Human ACP6 siRNA - orb270108 from Biorbyt
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ACP6 shRNA Plasmid (Human) - CHH9606 from Cohesion Biosciences
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ACP6 miRNA 3'UTR clone - MiUTR1H-00115 from Creative biogene
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