| Gene Symbol |
PDE3A
|
| Entrez Gene |
5139
|
| Alt Symbol |
CGI-PDE, CGI-PDE A, CGI-PDE-A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphodiesterase 3A, cGMP-inhibited
|
| Other Description |
cAMP phosphodiesterase, myocardial cGMP-inhibited|cGMP-inhibited 3',5'-cyclic phosphodiesterase A|cyclic GMP-inhibited phosphodiesterase A
|
| Swissprots |
O60865 Q14432 Q17RD1 Q13348
|
| Accessions |
EAW96406 Q14432 AJ005036 CAA06304 AK095203 AK308317 BC117369 AAI17370 BC117371 AAI17372 BQ024709 BQ187047 BX646774 M91667 AAA35912 U36798 AAB18673 XM_006719086 XP_006719149 NM_000921 NP_000912 NM_001244683 NP_001231612
|
| Function |
Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
| Top Pathways |
Morphine addiction, cGMP-PKG signaling pathway, cAMP signaling pathway, Purine metabolism
|