GAR1

Gene Symbol GAR1
Entrez Gene 54433
Alt Symbol NOLA1
Species Human
Gene Type protein-coding
Description GAR1 ribonucleoprotein
Other Description GAR1 ribonucleoprotein homolog|H/ACA ribonucleoprotein complex subunit 1|nucleolar protein family A member 1|nucleolar protein family A, member 1 (H/ACA small nucleolar RNPs)|snoRNP protein GAR1
Swissprots Q5MJQ2 Q9NY12
Accessions EAX06253 EAX06254 Q9NY12 AA311919 AJ276003 CAB76563 AK310489 AY780787 AAV98357 BC003413 AAH03413 CN428426 DQ894157 ABM85083 EU176271 ABW03722 NM_018983 NP_061856 NM_032993 NP_127460
Function Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. {ECO:0000269|PubMed:10757788, ECO:0000269|PubMed:15044956}.
Subcellular Location Nucleus, nucleolus. Nucleus, Cajal body. Note=Also localized to Cajal bodies (coiled bodies).
Top Pathways Ribosome biogenesis in eukaryotes

GAR1 ribonucleoprotein homolog (yeast) , ELISA Kit - MBS9324913 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human H/ACA ribonucleoprotein complex subunit 1 ELISA Kit - EKE52743 from Biomatik

Category ELISA Kit
Prices $685.40, $2,912.95, $5,483.20
Sizes 96 t, 5x96t, 10x96t
Range 0.78-50 ng/ml

Human H/ACA ribonucleoprotein complex subunit 1 ELISA Kit - EK2947 from Signalway Antibody

Category ELISA Kit
Prices $599.00
Sizes 1x96t
Range 0.78-50 ng/ml

H/ACA ribonucleoprotein complex subunit 1, ELISA Kit - MBS2887772 from MyBioSource

Category ELISA Kit
Prices $380.00, $500.00, $2,170.00, $3,840.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Range 0.78-50 ng/ml

H/ACA ribonucleoprotein complex subunit 1, ELISA Kit - MBS9426783 from MyBioSource

Category ELISA Kit
Prices $555.00
Sizes 96 tests
Range 0.78-50 ng/mL

H/ACA ribonucleoprotein complex subunit 1, ELISA Kit - MBS2887896 from MyBioSource

Category ELISA Kit
Prices $430.00, $570.00, $2,515.00, $4,520.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

H/ACA ribonucleoprotein complex subunit 1, ELISA Kit - MBS2887897 from MyBioSource

Category ELISA Kit
Prices $430.00, $570.00, $2,515.00, $4,520.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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