Gene Symbol | TH |
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Entrez Gene | 7054 |
Alt Symbol | DYT14, DYT5b, TYH |
Species | Human |
Gene Type | protein-coding |
Description | tyrosine hydroxylase |
Other Description | dystonia 14|tyrosine 3-hydroxylase|tyrosine 3-monooxygenase |
Swissprots | Q2M3B4 B7ZL70 B7ZL73 P07101 Q0PWM2 Q15585 Q15588 Q0PWM3 Q15589 |
Accessions | AAA61170 AAA61171 AAA61172 AAA61173 AAA77650 AAA77651 AAN73289 AAN73290 AAP43671 BAA25094 BAA25095 BAA25096 BAA25097 EAX02490 EAX02491 EAX02492 EAX02493 EAX02494 P07101 AA447751 AY144494 AAN39538 AY144495 AAN39539 BC104967 AAI04968 BC143611 AAI43612 BC143614 AAI43615 BM718799 DQ677336 ABG73364 DQ677337 ABG73365 M17589 AAA61179 M20911 AAA61167 M20912 AAA61168 M24790 AAA61174 X05290 CAA28908 Y00414 CAA68472 XM_011520335 XP_011518637 NM_000360 NP_000351 NM_199292 NP_954986 NM_199293 NP_954987 |
Function | Plays an important role in the physiology of adrenergic neurons. |
Tissue Specificity | Mainly expressed in the brain and adrenal glands. |
Top Pathways | Dopaminergic synapse, Amphetamine addiction, Cocaine addiction, Alcoholism, Prolactin signaling pathway |
TH CRISPR/Cas9 KO Plasmid (h) - sc-400273 from Santa Cruz Biotechnology
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TH HDR Plasmid (h) - sc-400273-HDR from Santa Cruz Biotechnology
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TH Double Nickase Plasmid (h) - sc-400273-NIC from Santa Cruz Biotechnology
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TH Double Nickase Plasmid (h2) - sc-400273-NIC-2 from Santa Cruz Biotechnology
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TH CRISPR Activation Plasmid (h) - sc-400273-ACT from Santa Cruz Biotechnology
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TH CRISPR Activation Plasmid (h2) - sc-400273-ACT-2 from Santa Cruz Biotechnology
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TH Lentiviral Activation Particles (h) - sc-400273-LAC from Santa Cruz Biotechnology
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TH Lentiviral Activation Particles (h2) - sc-400273-LAC-2 from Santa Cruz Biotechnology
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TH siRNA (h) - sc-36662 from Santa Cruz Biotechnology
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TH shRNA Plasmid (h) - sc-36662-SH from Santa Cruz Biotechnology
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TH shRNA (h) Lentiviral Particles - sc-36662-V from Santa Cruz Biotechnology
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Tyrosine Hydroxylase RNAi - H00007054-R03 from Novus Biologicals
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Tyrosine Hydroxylase RNAi - H00007054-R02 from Novus Biologicals
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MISSION® esiRNA - EHU095601 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2580 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2580 from Sigma-Aldrich
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TH siRNA (Human) - CRH4827 from Cohesion Biosciences
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Tyrosine Hydroxylase RNAi - H00007054-R01 from Novus Biologicals
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TH - MBS8218249 from MyBioSource
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TH CRISPR/Cas9 KO Plasmid (h2) - sc-400273-KO-2 from Santa Cruz Biotechnology
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TH HDR Plasmid (h2) - sc-400273-HDR-2 from Santa Cruz Biotechnology
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TH shRNA Plasmid (Human) - CHH4827 from Cohesion Biosciences
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TH miRNA 3'UTR clone - MiUTR1H-10366 from Creative biogene
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TH miRNA 3'UTR clone - MiUTR1H-10367 from Creative biogene
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TH miRNA 3'UTR clone - MiUTR1H-10368 from Creative biogene
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