ALCAM

Gene Symbol	ALCAM
Entrez Gene	214
Alt Symbol	CD166, MEMD
Species	Human
Gene Type	protein-coding
Description	activated leukocyte cell adhesion molecule
Other Description	CD166 antigen
Swissprots	Q1HGM9 B2RNS3 B4DTU0 Q1HGM8 Q13740 Q6PEY4 Q6ZS95 O60892
Accessions	EAW79755 EAW79756 EAW79757 Q13740 AB074167 AK054632 BAG51401 AK095833 AK127617 BAC87059 AK300362 BAG62102 AK301804 BAG63255 AK316113 BAH14484 AL833702 AY644765 AAV28819 BC029639 BC041127 BC057809 AAH57809 BC137096 AAI37097 BC137097 AAI37098 CA430528 CB145726 DA318514 DB541501 DQ486139 ABF48405 DQ486140 ABF48406 L38608 AAB59499 Y10183 CAA71256 NM_001243280 NP_001230209 NM_001243281 NP_001230210 NM_001243283 NP_001230212 NM_001627 NP_001618
Function	Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Spleen, placenta, liver, and weakly in liver. Expressed by activated T-cells, B-cells, monocytes and thymic epithelial cells. Expressed by neurons in the brain. Restricted expression in tumor cell lines. Preferentially expressed in highly metastasizing melanoma cell lines. {ECO:0000269|PubMed:9502422}.
Top Pathways	Cell adhesion molecules (CAMs)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CD166 full length protein - ab132286 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human CD166 protein fragment - ab112249 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human CD166 protein fragment - ab169878 from Abcam Category Protein Prices $456.00 Sizes 100 µg Source E. coli Species Human

Human CD166 protein fragment - ab191959 from Abcam Category Protein Prices $556.00 Sizes 200 µg Source HEK 293 cells Species Human

ALCAM / CD166 Antibody Blocking Peptide - LS-E7174 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ALCAM/CD166 Recombinant Protein - H00000214-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

ALCAM/CD166 Partial Recombinant Protein - H00000214-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

ALCAM/CD166 Recombinant Protein - H00000214-G01 from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

CD166-Antibody-N-term-Blocking-Peptide - BP2882a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human ALCAM Fc Chimera, CF - 656-AL-100 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Recombinant Human ALCAM Fc Chimera (HEK293-expressed), CF - 7187-AL-100 from R&D Systems Category Protein Source Human embryonic kidney cell, HEK293-derived

Recombinant human CD166 antigen (OPCA00860) - OPCA00860 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human CD166 His tag protein - orb83822 from Biorbyt Category Protein Prices $434.00, $612.00 Sizes 100 μg, 200 μg Source Human Species Human

CD166 protein - 30R-3142 from Fitzgerald Category Protein Prices $210.00 Sizes 50 µg Source E.coli

Human ALCAM Protein - abx065116 from Abbexa Category Protein Source E.coli Species Human

CD166 - H00000214-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

CD166 - H00000214-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CD166 - H00000214-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CD166 - H00000214-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CD166 - H00000214-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Activated Leukocyte Cell Adhesion Molecule (ALCAM), Human - 20-6002 from ARP American Research Products Category Protein Prices $329.00 Sizes 50 µg Source E.coli Species Human

ALCAM Recombinant Protein - 96-128 from ProSci Category Protein Prices $400.00 Sizes 200 µg Source HEK293 cells Species Human

ALCAM Recombinant Protein - 96-124 from ProSci Category Protein Prices $375.00 Sizes 200 µg Source HEK293 cells Species Human

ALCAM fusion protein - Ag17461 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

ALCAM fusion protein - Ag16892 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

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