Gene Symbol | ATP6V0A2 |
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Entrez Gene | 23545 |
Alt Symbol | A2, ARCL, ARCL2A, ATP6A2, ATP6N1D, J6B7, RTF, STV1, TJ6, TJ6M, TJ6S, VPH1, WSS |
Species | Human |
Gene Type | protein-coding |
Description | ATPase, H+ transporting, lysosomal V0 subunit a2 |
Other Description | A2V-ATPase|V-type proton ATPase 116 kDa subunit a isoform 2|lysosomal H(+)-transporting ATPase V0 subunit a2|regeneration and tolerance factor|v-ATPase 116 kDa|v-type proton ATPase 116 kDa subunit a|vacuolar proton translocating ATPase 116 kDa subunit a |
Swissprots | Q6NUM0 A8K026 Q9Y487 |
Accessions | EAW98434 EAW98436 Q9Y487 AF112972 AAD04632 AK056800 AK289391 BAF82080 AK298778 BAG60919 BC000826 BC022300 AAH22300 BC068531 AAH68531 BG106215 BG167832 BG759946 BI562012 BQ050095 BX328381 CB960860 CD654920 DA737084 HQ258004 ADR82758 R51339 XM_005253563 XP_005253620 XM_006719317 XP_006719380 XM_006719318 XP_006719381 XR_429088 NM_012463 NP_036595 |
Function | Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH. {ECO:0000269|PubMed:16415858, ECO:0000269|PubMed:18157129}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. Endosome membrane. Note=In kidney proximal tubules, also detected in subapical vesicles. {ECO:0000250}. |
Top Pathways | Collecting duct acid secretion, Tuberculosis, Synaptic vesicle cycle, Rheumatoid arthritis, Phagosome |
V-ATPase A2 (D-18) - sc-69092 from Santa Cruz Biotechnology
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V-ATPase A2 (N-14) - sc-69094 from Santa Cruz Biotechnology
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V-ATPase A2 (Y-20) - sc-69095 from Santa Cruz Biotechnology
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Anti-ATP6V0A2 Antibody (aa156-434) - LS-C186142 from LifeSpan Bioscience
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Anti-ATP6V0A2 Antibody (N-Terminus) - LS-C345308 from LifeSpan Bioscience
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Anti-ATP6V0A2 Antibody (aa72-121) IHC-plus™ - LS-B3548 from LifeSpan Bioscience
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ATP6V0A2 Antibody - NBP1-59069 from Novus Biologicals
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ATP6V0A2 Antibody - NBP1-91690 from Novus Biologicals
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ATP6V0A2 Antibody - NBP1-33018 from Novus Biologicals
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ATP6V0A2 Antibody - NBP2-15516 from Novus Biologicals
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ATP6V0A2 Antibody - H00023545-A01 from Novus Biologicals
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Anti-ATP6V0A2 antibody produced in rabbit - HPA044279 from Sigma-Aldrich
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Anti-ATP6V0A2 antibody produced in rabbit - SAB2100187 from Sigma-Aldrich
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Anti-ATP6V0A2 antibody produced in rabbit - SAB2701090 from Sigma-Aldrich
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Anti-ATP6V0A2 antibody produced in rabbit - SAB2701067 from Sigma-Aldrich
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ATP6V0A2 antibody - N-terminal region (ARP42365_P050) - ARP42365_P050 from Aviva Systems Biology
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ATP6V0A2 Antibody - N-terminal region (ARP73759_P050) - ARP73759_P050 from Aviva Systems Biology
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ATP6V0A2 antibody [N1N3] - GTX111275 from GeneTex
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ATP6V0A2 antibody [N2C1], Internal - GTX110248 from GeneTex
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Hemoglobin antibody - orb24649 from Biorbyt
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ATP6V0A2 antibody - orb73791 from Biorbyt
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VATPase a4 antibody - 70R-13413 from Fitzgerald
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ATP6V0A2 antibody - 70R-13352 from Fitzgerald
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ATP6V0A2 antibody - orb154891 from Biorbyt
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ATP6V0A2 antibody - 70R-5999 from Fitzgerald
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