Gene Symbol | ATP6V0A2 |
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Entrez Gene | 23545 |
Alt Symbol | A2, ARCL, ARCL2A, ATP6A2, ATP6N1D, J6B7, RTF, STV1, TJ6, TJ6M, TJ6S, VPH1, WSS |
Species | Human |
Gene Type | protein-coding |
Description | ATPase, H+ transporting, lysosomal V0 subunit a2 |
Other Description | A2V-ATPase|V-type proton ATPase 116 kDa subunit a isoform 2|lysosomal H(+)-transporting ATPase V0 subunit a2|regeneration and tolerance factor|v-ATPase 116 kDa|v-type proton ATPase 116 kDa subunit a|vacuolar proton translocating ATPase 116 kDa subunit a |
Swissprots | Q6NUM0 A8K026 Q9Y487 |
Accessions | EAW98434 EAW98436 Q9Y487 AF112972 AAD04632 AK056800 AK289391 BAF82080 AK298778 BAG60919 BC000826 BC022300 AAH22300 BC068531 AAH68531 BG106215 BG167832 BG759946 BI562012 BQ050095 BX328381 CB960860 CD654920 DA737084 HQ258004 ADR82758 R51339 XM_005253563 XP_005253620 XM_006719317 XP_006719380 XM_006719318 XP_006719381 XR_429088 NM_012463 NP_036595 |
Function | Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH. {ECO:0000269|PubMed:16415858, ECO:0000269|PubMed:18157129}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. Endosome membrane. Note=In kidney proximal tubules, also detected in subapical vesicles. {ECO:0000250}. |
Top Pathways | Collecting duct acid secretion, Tuberculosis, Synaptic vesicle cycle, Rheumatoid arthritis, Phagosome |
Human ATP6V0A2 full length protein - ab153236 from Abcam
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Human ATP6V0A2 protein fragment - ab153237 from Abcam
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ATP6V0A2 Antibody Blocking Peptide - LS-E15589 from LifeSpan Bioscience
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ATP6V0A2 Recombinant Protein - H00023545-P01 from Novus Biologicals
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ATP6V0A2 Partial Recombinant Protein - H00023545-Q01 from Novus Biologicals
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ATP6V0A2-Antibody-Center-Blocking-Peptide - BP5110c from Abgent, a WuXi AppTec company
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ATP6V0A2 Blocking Peptide - 33R-4080 from Fitzgerald
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ATP6V0A2 Blocking Peptide - abx161288 from Abbexa
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ATP6V0A2 - H00023545-P01-10 from Acris Antibodies
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ATP6V0A2 - H00023545-P01-25 from Acris Antibodies
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ATP6V0A2 - H00023545-Q01-10 from Acris Antibodies
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ATP6V0A2 - H00023545-Q01-25 from Acris Antibodies
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ATP6V0A2 fusion protein - Ag9554 from Proteintech Group
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ATP6V0A2 fusion protein - ag9549 from Proteintech Group
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Recombinant Human ATP, His-tagged - ATP6V0A2-10034H from Creative Biomart
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ATP6V0A2 Blocking Peptide - CBP3787 from Cohesion Biosciences
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Recombinant T-Cell, Immune Regulator 1 (TCIRG1) - RPM347Hu01 from Cloud-clone
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Protein A2, Recombinant Protein - MBS1126260 from MyBioSource
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ATP6V0A2 Recombinant Protein Antigen - NBP1-91690PEP from Novus Biologicals
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ATP6V0A2 Peptide, Human - M34GP01175H from Creative Peptides
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