| Gene Symbol |
ALG11
|
| Entrez Gene |
440138
|
| Alt Symbol |
CDG1P, GT8
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ALG11, alpha-1,2-mannosyltransferase
|
| Other Description |
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase|GDP-Man:Man(3)GlcNAc(2)-PP-dolichol alpha-1,2-mannosyltransferase|asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog|asparagine-linked glycosylation protein 11 homolog|glycolipid 2-alpha-mannosyltransferase
|
| Swissprots |
Q6DKI6 A5PLP3 Q96FI7 Q5TAN9 Q2TAA5 B4DKW9
|
| Accessions |
CBX51363 Q2TAA5 AK025456 AK128503 AK296747 BAG59331 BC010857 AAH10857 BC073862 AAH73862 BC108677 BC111022 AAI11023 BC142998 AAI42999 BC143059 AAI43060 BC150316 AAI50317 BP373026 DC366525 NM_001004127 NP_001004127 NR_036571
|
| Function |
Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th mannose residues to the dolichol- linked oligosaccharide chain. {ECO:0000269|PubMed:20080937}.
|
| Subcellular Location |
Endoplasmic reticulum {ECO:0000269|PubMed:20080937}. Endoplasmic reticulum membrane {ECO:0000305|PubMed:20080937}; Multi-pass membrane protein {ECO:0000305|PubMed:20080937}.
|
| Top Pathways |
N-Glycan biosynthesis
|
![Western Blot: ALG11 Overexpression Lysate (Adult Normal) [NBP2-08931] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ALG11.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/16098_ALG11%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-08931-img0001.jpg)