Gene Symbol | ALG11 |
---|---|
Entrez Gene | 440138 |
Alt Symbol | CDG1P, GT8 |
Species | Human |
Gene Type | protein-coding |
Description | ALG11, alpha-1,2-mannosyltransferase |
Other Description | GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase|GDP-Man:Man(3)GlcNAc(2)-PP-dolichol alpha-1,2-mannosyltransferase|asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog|asparagine-linked glycosylation protein 11 homolog|glycolipid 2-alpha-mannosyltransferase |
Swissprots | Q6DKI6 A5PLP3 Q96FI7 Q5TAN9 Q2TAA5 B4DKW9 |
Accessions | CBX51363 Q2TAA5 AK025456 AK128503 AK296747 BAG59331 BC010857 AAH10857 BC073862 AAH73862 BC108677 BC111022 AAI11023 BC142998 AAI42999 BC143059 AAI43060 BC150316 AAI50317 BP373026 DC366525 NM_001004127 NP_001004127 NR_036571 |
Function | Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th mannose residues to the dolichol- linked oligosaccharide chain. {ECO:0000269|PubMed:20080937}. |
Subcellular Location | Endoplasmic reticulum {ECO:0000269|PubMed:20080937}. Endoplasmic reticulum membrane {ECO:0000305|PubMed:20080937}; Multi-pass membrane protein {ECO:0000305|PubMed:20080937}. |
Top Pathways | N-Glycan biosynthesis |
ALG11 CRISPR/Cas9 KO Plasmid (h) - sc-408368 from Santa Cruz Biotechnology
|
||||||||
ALG11 HDR Plasmid (h) - sc-408368-HDR from Santa Cruz Biotechnology
|
||||||||
ALG11 Double Nickase Plasmid (h) - sc-408368-NIC from Santa Cruz Biotechnology
|
||||||||
ALG11 Double Nickase Plasmid (h2) - sc-408368-NIC-2 from Santa Cruz Biotechnology
|
||||||||
ALG11 CRISPR Activation Plasmid (h) - sc-408368-ACT from Santa Cruz Biotechnology
|
||||||||
ALG11 CRISPR Activation Plasmid (h2) - sc-408368-ACT-2 from Santa Cruz Biotechnology
|
||||||||
ALG11 Lentiviral Activation Particles (h) - sc-408368-LAC from Santa Cruz Biotechnology
|
||||||||
ALG11 Lentiviral Activation Particles (h2) - sc-408368-LAC-2 from Santa Cruz Biotechnology
|
||||||||
ALG11 siRNA (h) - sc-105053 from Santa Cruz Biotechnology
|
||||||||
ALG11 shRNA Plasmid (h) - sc-105053-SH from Santa Cruz Biotechnology
|
||||||||
ALG11 shRNA (h) Lentiviral Particles - sc-105053-V from Santa Cruz Biotechnology
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN3054 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3054 from Sigma-Aldrich
|
||||||||
ALG11 siRNA (Human) - CRJ8238 from Cohesion Biosciences
|
||||||||
ALG11 - MBS8236475 from MyBioSource
|
||||||||
shRNA set against Human ALG11 (NM_001004127.2) - SHH235074 from Creative biogene
|
||||||||
Human ALG11 siRNA - orb278739 from Biorbyt
|
||||||||
ALG11 shRNA Plasmid (Human) - CHJ8238 from Cohesion Biosciences
|
||||||||
ALG11 miRNA 3'UTR clone - MiUTR3H-12999 from Creative biogene
|