Gene Symbol | PAXBP1 |
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Entrez Gene | 94104 |
Alt Symbol | BM020, C21orf66, FSAP105, GCFC, GCFC1 |
Species | Human |
Gene Type | protein-coding |
Description | PAX3 and PAX7 binding protein 1 |
Other Description | GC-rich sequence DNA-binding factor 1|GC-rich sequence DNA-binding factor candidate|PAX3- and PAX7-binding protein 1|functional spliceosome-associated protein 105 |
Swissprots | D3DSE7 Q9Y5B6 Q96DU8 Q9NYQ0 |
Accessions | EAX09857 EAX09858 EAX09859 EAX09860 EAX09861 Q9Y5B6 AF153208 AAD34617 AF208862 AAF64276 AF231920 AAF72944 AJ279080 CAC40813 AJ279081 CAC40814 AK075042 BAC11369 AK093291 BAG52682 AK128513 BAG54687 AK309404 AL706425 AY033903 AAK68721 AY033904 AAK68722 AY033905 AAK68723 AY033906 AAK68724 BC005213 BC030539 AAH30539 BC062992 BC084542 AAH84542 BC156214 AAI56215 CD557070 DB031308 DQ891624 ABM82550 DQ894815 ABM85741 XM_006724066 XP_006724129 XM_006724067 XP_006724130 XM_011529804 XP_011528106 XM_011529805 XP_011528107 NM_013329 NP_037461 NM_016631 NP_057715 NR_027873 NM_058191 NM_145328 |
Function | Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with an histone methyltransferase complex that specifically mediates dimethylation and trimethylation of 'Lys-4' of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20 (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:11707072}. |
GCFC1 (E-16) - sc-83567 from Santa Cruz Biotechnology
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Anti- C21orf66 antibody - ab67637 from Abcam
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Anti-C21orf66 antibody - ab176590 from Abcam
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Anti-PAXBP1 / GCFC1 Antibody (AP) - LS-C222602 from LifeSpan Bioscience
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Anti-PAXBP1 / GCFC1 Antibody (Biotin) - LS-C222604 from LifeSpan Bioscience
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Anti-PAXBP1 / GCFC1 Antibody (APC) - LS-C222603 from LifeSpan Bioscience
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Anti-PAXBP1 / GCFC1 Antibody (FITC) - LS-C222605 from LifeSpan Bioscience
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Anti-PAXBP1 / GCFC1 Antibody (Azide-free, HRP) - LS-C222606 from LifeSpan Bioscience
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Anti-PAXBP1 / GCFC1 Antibody (PE) - LS-C222607 from LifeSpan Bioscience
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Anti-PAXBP1 / GCFC1 Antibody (aa275-325) - LS-C289866 from LifeSpan Bioscience
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Anti-PAXBP1 / GCFC1 Antibody (C-Terminus) - LS-C81098 from LifeSpan Bioscience
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Anti-PAXBP1 / GCFC1 Antibody (aa225-275) - LS-C289865 from LifeSpan Bioscience
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Anti-PAXBP1 / GCFC1 Antibody (aa867-917) - LS-C289867 from LifeSpan Bioscience
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Anti-PAXBP1 / GCFC1 Antibody (Internal) - LS-C321581 from LifeSpan Bioscience
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Anti-PAXBP1 / GCFC1 Antibody (aa216-265) - LS-C81097 from LifeSpan Bioscience
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Anti-PAXBP1 / GCFC1 Antibody (aa141-190) - LS-C120000 from LifeSpan Bioscience
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GCFC1 Antibody - NBP1-86818 from Novus Biologicals
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GCFC1 Antibody - H00094104-B01P from Novus Biologicals
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GCFC1 Antibody - NBP1-71923 from Novus Biologicals
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GCFC1 Antibody - NBP1-71922 from Novus Biologicals
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GCFC1 Antibody - NBP1-71921 from Novus Biologicals
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Anti-C21ORF66 (ab1) antibody produced in rabbit - SAB2100288 from Sigma-Aldrich
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Anti-GCFC (center) antibody produced in rabbit - SAB1300605 from Sigma-Aldrich
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Anti-C21ORF66 (ab2) antibody produced in rabbit - SAB2100289 from Sigma-Aldrich
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Anti-GCFC (C-term) antibody produced in rabbit - SAB1300604 from Sigma-Aldrich
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