RAD17

Gene Symbol RAD17
Entrez Gene 5884
Alt Symbol CCYC, HRAD17, R24L, RAD17SP, RAD24
Species Human
Gene Type protein-coding
Description RAD17 homolog (S. pombe)
Other Description RAD1 homolog|RF-C activator 1 homolog|RF-C/activator 1 homolog|Rad17-like protein|cell cycle checkpoint protein (RAD17)|cell cycle checkpoint protein RAD17
Swissprots Q7Z3S4 Q9UNR7 O75714 Q9UPF5 O75943 D3DWA5 A8K8X2 Q9UNK7 Q9UNR8
Accessions AAD42176 AAT09763 CAB46364 EAW51279 EAW51280 EAW51281 EAW51282 EAW51283 EAW51284 EAW51285 EAW51286 EAW51287 EAW51288 EAW51289 O75943 AF017748 AAD01620 AF076838 AAC95520 AF085736 AAC36334 AF098533 AAC97950 AF098534 AAC97951 AF112263 AAD38878 AF126424 AAD17334 AJ001642 CAA04894 AJ004977 CAA06251 AK292487 BAF85176 AL122068 CAB59244 AM393045 CAL37923 BC018110 BC032304 AAH32304 BX537441 CAD97683 DQ891608 ABM82534 DQ894801 ABM85727 XM_005276774 XP_005276831 XM_011546954 XP_011545256 XM_011546955 XP_011545257 NM_001278622 NP_001265551 NM_002873 NP_002864 NM_133338 NP_579916 NM_133339 NP_579917 NM_133340 NP_579918 NM_133341 NP_579919 NM_133342 NP_579920 NM_133343 NP_579921 NM_133344 NP_579922
Function Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Has a weak ATPase activity required for binding to chromatin. Participates in the recruitment of the RAD1-RAD9- HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination. {ECO:0000269|PubMed:10208430, ECO:0000269|PubMed:11418864, ECO:0000269|PubMed:11687627, ECO:0000269|PubMed:11799063, ECO:0000269|PubMed:12578958, ECO:0000269|PubMed:12672690, ECO:0000269|PubMed:14500819, ECO:0000269|PubMed:14624239, ECO:0000269|PubMed:15235112, ECO:0000269|PubMed:15538388, ECO:0000269|PubMed:21659603}.
Subcellular Location Nucleus {ECO:0000269|PubMed:10232579, ECO:0000269|PubMed:10593953, ECO:0000269|PubMed:11799063, ECO:0000269|PubMed:12400013}. Note=Phosphorylated form redistributes to discrete nuclear foci upon DNA damage.
Tissue Specificity Overexpressed in various cancer cell lines and in colon carcinoma (at protein level). Isoform 2 and isoform 3 are the most abundant isoforms in non irradiated cells (at protein level). Ubiquitous at low levels. Highly expressed in testis, where it is expressed within the germinal epithelium of the seminiferous tubuli. Weakly expressed in seminomas (testicular tumors). {ECO:0000269|PubMed:10208430, ECO:0000269|PubMed:10232579, ECO:0000269|PubMed:10480350, ECO:0000269|PubMed:11602352, ECO:0000269|PubMed:9660800}.

Mouse/Human Phospho-RAD17 (Ser645) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1099 from LifeSpan Bioscience

Category ELISA Kit
Prices $550.00
Sizes 1 plate

Mouse/Human RAD17 ELISA Kit (Cell-Based ELISA) - LS-F2278 from LifeSpan Bioscience

Category ELISA Kit
Prices $450.00
Sizes 1 plate

Goat anti-Rad17 Antibody, Affinity Purified - PLA0051 from Sigma-Aldrich

Prices $323.50
Sizes 100 µl
<B>Immunofluorescence</B>: This antibody is qualified for the Proximity Ligation Assay (PLA). The above image shows representative results for PLA using three color fluorescence, including DAPI stained nuclei (blue), phalloidin stained cytoplasmic F-actin (green), and PLA positive signal (red).

Rabbit anti-Phospho Rad17 (S645) Antibody, Affinity Purified - PLA0052 from Sigma-Aldrich

Prices $345.00
Sizes 100 µl
<B>Immunofluorescence</B>: This antibody is qualified for the Proximity Ligation Assay (PLA). The above image shows representative results for PLA using three color fluorescence, including DAPI stained nuclei (blue), phalloidin stained cytoplasmic F-actin (green), and PLA positive signal (red).

Cell cycle checkpoint protein RAD17 (RAD17), Human, ELISA Kit - E01C2413 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

RAD17 Colorimetric Cell-Based ELISA Kit - CB5597 from Assay Biotechnology

Category ELISA Kit
Prices $380.00, $760.00, $1,140.00
Sizes 1 kit, 2 kits, 3 kits
Range > 5000 Cells

RAD17 (Phospho-Ser645) Colorimetric Cell-Based ELISA Kit - CBP1078 from Assay Biotechnology

Category ELISA Kit
Prices $480.00, $960.00, $1,440.00
Sizes 1 kit, 2 kits, 3 kits
Range > 5000 Cells

Cell cycle checkpoint protein RAD17 (RAD17), ELISA Kit - MBS7233035 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell cycle checkpoint protein RAD17 (RAD17), ELISA Kit - MBS7244815 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell cycle checkpoint protein RAD17 (RAD17), ELISA Kit - MBS7205395 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell cycle checkpoint protein RAD17 (RAD17), ELISA Kit - MBS7247410 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell cycle checkpoint protein RAD17 (RAD17), ELISA Kit - MBS7249498 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell cycle checkpoint protein RAD17 (RAD17), ELISA Kit - MBS7227283 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell cycle checkpoint protein RAD17 (RAD17), ELISA Kit - MBS7211679 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell cycle checkpoint protein RAD17 (RAD17), ELISA Kit - MBS7216297 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell cycle checkpoint protein RAD17 (RAD17), ELISA Kit - MBS7215536 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell cycle checkpoint protein RAD17 (RAD17), ELISA Kit - MBS7214272 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell cycle checkpoint protein RAD17 (RAD17), ELISA Kit - MBS7208131 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cell cycle checkpoint protein RAD17 (RAD17), ELISA Kit - MBS7242948 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ractopamine, Rac, ELISA Kit - MBS9301000 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

RAD17 ELISA Kit - DEIA-XYA1523 from Creative Diagnostics

Category ELISA Kit

RAD17 (Phospho-Ser645) ELISA Kit - DEIA-XYA1524 from Creative Diagnostics

Category ELISA Kit

Human RAD17 ELISA Kit - E007651 from Biobool

Category ELISA Kit

anti-Rad17 antibody - ARG56300 from Arigo Biolaboratories

Category ELISA Kit

RAD17 Colorimetric Cell-Based ELISA Kit - EKA50513 from Biomatik

Category ELISA Kit
Prices $399.00
Sizes 96 tests
Sensitivity At least 5000 cells/well
Range Qualitative
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