| Gene Symbol | GH2 |
|---|---|
| Entrez Gene | 2689 |
| Alt Symbol | GH-V, GHL, GHV, hGH-V |
| Species | Human |
| Gene Type | protein-coding |
| Description | growth hormone 2 |
| Other Description | growth hormone variant|placenta-specific growth hormone|placental-specific growth hormone |
| Swissprots | P09587 B1A4H7 O14644 B1A4H5 O14643 P01242 |
| Accessions | AAA52552 AAA98619 ABZ88719 ABZ88720 ABZ88721 ABZ88722 EAW94238 EAW94248 EAW94252 EAW94258 P01242 AB451332 BAG70146 AB451477 BAG70291 AF006060 AAB71828 AF006061 AAB71829 AK312194 BAG35127 AU139016 BC020760 AAH20760 CF528273 CR541902 CAG46700 CR541924 CAG46722 J03756 AAB59547 M38451 AAA35891 NM_002059 NP_002050 NM_022556 NP_072050 NM_022557 NP_072051 NM_022558 NP_072052 |
| Function | Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. |
| Subcellular Location | Secreted. |
| Tissue Specificity | Expressed in the placenta. |
| Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, PI3K-Akt signaling pathway, Neuroactive ligand-receptor interaction |