PXYLP1

Gene Symbol	PXYLP1
Entrez Gene	92370
Alt Symbol	ACPL2, HEL124, XYLP
Species	Human
Gene Type	protein-coding
Description	2-phosphoxylose phosphatase 1
Other Description	acid phosphatase-like 2|acid phosphatase-like protein 2|epididymis luminal protein 124|xylosyl phosphatase
Swissprots	Q8TE99 D3DNF5 W0TR04 Q49AJ2
Accessions	EAW79007 EAW79008 EAW79009 Q8TE99 AB827640 BAO45795 AK074331 BAB85053 AK296292 BAH12305 AK297790 BAH12668 AK316121 BAH14492 AL137529 CAB70793 AY358460 AAQ88825 BC035834 AAH35834 BC036701 AAH36701 BX647621 CA421956 CD101677 CX762355 DC409719 EU794677 ACJ13731 XM_005247903 XP_005247960 XM_011513314 XP_011511616 XM_011513315 XP_011511617 XM_011513316 XP_011511618 NM_001037172 NP_001032249 NM_001282728 NP_001269657 NM_152282 NP_689495
Function	Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1- 4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains. {ECO:0000269|PubMed:24425863}.
Subcellular Location	Golgi apparatus membrane {ECO:0000269|PubMed:24425863}; Single-pass type II membrane protein {ECO:0000255}. Note=Colocalizes to Golgi apparatus in a B3GAT3-dependent manner. {ECO:0000269|PubMed:24425863}.
Tissue Specificity	Widely expressed. Strongly expressed in spleen, fetal liver, moderately in placenta, pancreas, kidney, thymus and colon. {ECO:0000269|PubMed:24425863}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PXYLP1 / ACPL2 Antibody Blocking Peptide - LS-E4069 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PXYLP1 / ACPL2 Antibody Blocking Peptide - LS-E16467 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PXYLP1 / ACPL2 Antibody Blocking Peptide - LS-E16468 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ACPL2-Antibody-Center-Blocking-Peptide - BP16304c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human ACPL2 His tag protein - orb83832 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source Human Species Human

ACPL2 Blocking Peptide - 33R-8424 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ACPL2 Blocking Peptide - 33R-7377 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ACPL2 fusion protein - ag11364 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ACPL2 fusion protein - Ag11674 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human ACPL2, His tagged - ACPL2-3239H from Creative Biomart Category Protein Source Human Cells Species Human

ACPL2 - PN201227 from Elabscience Category Protein Prices $225.00, $475.00 Sizes 10 μg, 50 μg Source Human Cells Species Human

Human ACPL2 Protein (His Tag) - 11243-H08H-100 from Sino Biological Category Protein Source Human Cells Species Human

Recombinant Human Acid phosphatase-like protein 2(ACPL2) - CSB-YP848416HU CSB-EP848416HU CSB-BP848416HU CSB-MP848416HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Acid shock protein (asr) - MBS1452336 from MyBioSource Category Protein Prices $2,015.00, $2,015.00, $2,480.00, $2,480.00 Sizes 1 mg (E Coli Derived), 100 µg (Baculovirus Derived), 1 mg (Yeast Derived), 100 µg (Mammalian Cell Derived) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human ACPL2 Protein (His tag) - PKSH031183 from Elabscience Category Protein Source Human Cell Species Human

ACPL2 Recombinant Protein Antigen - NBP1-83577PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ACPL2 Peptide, Human - M34GP00158H from Creative Peptides Category Peptide Source Synthetic. Species Human

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