GAN

Gene Symbol	GAN
Entrez Gene	8139
Alt Symbol	GAN1, KLHL16
Species	Human
Gene Type	protein-coding
Description	gigaxonin
Other Description	kelch-like family member 16|kelch-like protein 16
Swissprots	Q9H2C0
Accessions	EAW95535 Q9H2C0 AF291673 AAG35311 AK095378 BAG53035 BC016717 BC044840 AAH44840 HQ257897 ADR82652 NM_022041 NP_071324
Function	Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival. {ECO:0000269|PubMed:12147674, ECO:0000269|PubMed:15983046, ECO:0000269|PubMed:16227972, ECO:0000269|PubMed:16303566}.
Subcellular Location	Cytoplasm. Cytoplasm, cytoskeleton.
Tissue Specificity	Expressed in brain, heart and muscle. {ECO:0000269|PubMed:12147674}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-GAN-cDNA-Clone - DC07559 from Abgent, a WuXi AppTec company Prices $805.95 Sizes 10 µg Species Human Accession BC044840

GAN - MBS1276892 from MyBioSource Species Human Accession BC044840

Human GAN ORF clone - CDCL110593 from Creative Biomart Species Human Accession NM_022041

Human GAN ORF clone - CDCL110594 from Creative Biomart Species Human Accession NM_022041

Human GAN ORF Clone(NM_022041.3) - CDCL164327 from Creative Biomart Species Human Accession NM_022041.3

Human GAN ORF Clone(NM_022041.3) - CDCR307422 from Creative Biomart Species Human Accession NM_022041.3

Human GAN ORF Clone(NM_022041.3) - CDCR307423 from Creative Biomart Species Human Accession NM_022041.3

Human GAN ORF Clone(NM_022041.3) - CDCR307422 from Creative biogene Species Human

Human GAN ORF Clone (BC044840) - CDCS415412 from Creative biogene Species Human Accession Q9H2C0

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