GAN

Gene Symbol	GAN
Entrez Gene	8139
Alt Symbol	GAN1, KLHL16
Species	Human
Gene Type	protein-coding
Description	gigaxonin
Other Description	kelch-like family member 16|kelch-like protein 16
Swissprots	Q9H2C0
Accessions	EAW95535 Q9H2C0 AF291673 AAG35311 AK095378 BAG53035 BC016717 BC044840 AAH44840 HQ257897 ADR82652 NM_022041 NP_071324
Function	Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival. {ECO:0000269|PubMed:12147674, ECO:0000269|PubMed:15983046, ECO:0000269|PubMed:16227972, ECO:0000269|PubMed:16303566}.
Subcellular Location	Cytoplasm. Cytoplasm, cytoskeleton.
Tissue Specificity	Expressed in brain, heart and muscle. {ECO:0000269|PubMed:12147674}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Gigaxonin full length protein - ab132335 from Abcam Category Protein Source Wheat germ Species Human

Human Gigaxonin peptide - ab28136 from Abcam Category Peptide

Human Gigaxonin protein fragment - ab159950 from Abcam Category Protein Source Wheat germ Species Human

GAN Antibody Blocking Peptide - LS-E21389 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Gigaxonin Protein - H00008139-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Gigaxonin Protein - H00008139-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

GAN Blocking Peptide - 33R-4223 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Kelch-like protein 16 - H00008139-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Kelch-like protein 16 - H00008139-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Kelch-like protein 16 - H00008139-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Kelch-like protein 16 - H00008139-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

GAN fusion protein - Ag5421 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

GAN fusion protein - ag5426 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human GAN, His-tagged - GAN-13149H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Gigaxonin (GAN) - RPJ068Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Gigaxonin (GAN) - RPJ068Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Gigaxonin(GAN) - CSB-YP009228HU CSB-EP009228HU CSB-BP009228HU CSB-MP009228HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Gigaxonin Protein (Recombinant) - abx166536 from Abbexa Category Protein Source Human Species Human

Gigaxonin Recombinant Protein Antigen - NBP2-33569PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

GAN-Antibody-Center-H205-Blocking-Peptide - BP6726c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GAN Peptide, Human - M34GP06099H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Gigaxonin (GAN) - RPU51630 from Biomatik Category Protein Prices $176.00, $360.00, $550.00, $656.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

GAN Recombinant Protein (OPCD03431) - OPCD03431 from Aviva Systems Biology Category Protein Source E.coli Species Human

Gigaxonin, Recombinant Protein - MBS2030466 from MyBioSource Category Protein Prices $175.00, $360.00, $560.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

Gigaxonin (GAN), Recombinant Protein - MBS1434720 from MyBioSource Category Protein Prices $1,400.00, $1,400.00, $1,615.00, $1,615.00, $2,340.00, $2,340.00, $2,780.00, $2,780.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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