GAN

Gene Symbol GAN
Entrez Gene 8139
Alt Symbol GAN1, KLHL16
Species Human
Gene Type protein-coding
Description gigaxonin
Other Description kelch-like family member 16|kelch-like protein 16
Swissprots Q9H2C0
Accessions EAW95535 Q9H2C0 AF291673 AAG35311 AK095378 BAG53035 BC016717 BC044840 AAH44840 HQ257897 ADR82652 NM_022041 NP_071324
Function Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival. {ECO:0000269|PubMed:12147674, ECO:0000269|PubMed:15983046, ECO:0000269|PubMed:16227972, ECO:0000269|PubMed:16303566}.
Subcellular Location Cytoplasm. Cytoplasm, cytoskeleton.
Tissue Specificity Expressed in brain, heart and muscle. {ECO:0000269|PubMed:12147674}.

Gigaxonin CRISPR/Cas9 KO Plasmid (h) - sc-407001 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Gigaxonin HDR Plasmid (h) - sc-407001-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Gigaxonin Double Nickase Plasmid (h) - sc-407001-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Gigaxonin Double Nickase Plasmid (h2) - sc-407001-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Gigaxonin CRISPR Activation Plasmid (h) - sc-407001-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Gigaxonin CRISPR Activation Plasmid (h2) - sc-407001-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Gigaxonin Lentiviral Activation Particles (h) - sc-407001-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Gigaxonin Lentiviral Activation Particles (h2) - sc-407001-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Gigaxonin siRNA (h) - sc-60687 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Gigaxonin shRNA Plasmid (h) - sc-60687-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Gigaxonin shRNA (h) Lentiviral Particles - sc-60687-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Gigaxonin RNAi - H00008139-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU032341 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9125 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9125 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GAN siRNA (Human) - CRH5378 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GAN - MBS8201806 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Gigaxonin CRISPR/Cas9 KO Plasmid (h2) - sc-407001-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Gigaxonin HDR Plasmid (h2) - sc-407001-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human GAN (NM_022041.3) - SHH299245 from Creative biogene

Category siRNA
Species Reactivities Human

Human GAN siRNA - orb265880 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GAN shRNA Plasmid (Human) - CHH5378 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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