Gene Symbol |
med4
|
Entrez Gene |
550582
|
Alt Symbol |
zgc:110646
|
Species |
Zebrafish
|
Gene Type |
protein-coding
|
Description |
mediator complex subunit 4
|
Other Description |
mediator of RNA polymerase II transcription subunit 4
|
Swissprots |
Q561X3
|
Accessions |
Q561X3 BC092965 AAH92965 BC164333 AAI64333 NM_001017883 NP_001017883
|
Function |
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). {ECO:0000250}.
|
Subcellular Location |
Nucleus {ECO:0000250}.
|