| Gene Symbol | POLM |
|---|---|
| Entrez Gene | 27434 |
| Alt Symbol | Pol Mu, Tdt-N |
| Species | Human |
| Gene Type | protein-coding |
| Description | polymerase (DNA directed), mu |
| Other Description | DNA polymerase mu|DNA-directed DNA/RNA polymerase mu|Pol iota|polymerase (DNA-directed), mu|terminal transferase |
| Swissprots | Q6P5X8 Q9NP87 Q86WQ9 D3DVK4 |
| Accessions | AAW65376 EAW61120 EAW61121 EAW61122 EAW61123 EAW61124 EAW61125 EAW61126 EAW61127 Q9NP87 AA917987 AF176097 AAF26284 AJ131891 CAB65075 AK023002 BAB14353 AK092801 AK092903 AK291638 BAF84327 AK294449 BAG57686 AK307634 AU309799 BC026306 AAH26306 BC035685 BC049202 AAH49202 BC062590 AAH62590 BI001584 DC407437 XM_005249711 XP_005249768 XM_006715692 XP_006715755 XM_006715693 XP_006715756 XM_006715696 XP_006715759 XM_006715697 XP_006715760 XM_006715698 XP_006715761 XM_011515275 XP_011513577 XM_011515276 XP_011513578 XM_011515277 XP_011513579 XM_011515278 XP_011513580 XM_011515279 XP_011513581 XM_011515280 XP_011513582 XM_011515281 XP_011513583 XM_011515282 XP_011513584 XM_011515283 XP_011513585 XM_011515284 XP_011513586 XM_011515285 XP_011513587 XM_011515286 XP_011513588 XM_011515287 XP_011513589 XR_926931 XR_926932 XR_926933 NM_001284330 NP_001271259 NM_001284331 NP_001271260 NM_013284 NP_037416 NR_104299 |
| Function | Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. {ECO:0000269|PubMed:12640116, ECO:0000269|PubMed:12888504, ECO:0000269|PubMed:17483519, ECO:0000269|PubMed:17915942}. |
| Subcellular Location | Nucleus {ECO:0000250}. |
| Tissue Specificity | Expressed in a number of tissues. Abundant in thymus. |
| Top Pathways | Non-homologous end-joining |