CDC42SE2

Gene Symbol	CDC42SE2
Entrez Gene	56990
Alt Symbol	SPEC2
Species	Human
Gene Type	protein-coding
Description	CDC42 small effector 2
Other Description	CDC42 small effector protein 2|non-kinase Cdc42 effector protein SPEC2|small effector of CDC42 protein 2
Swissprots	Q9NRR3 Q4KMT9 B2R622
Accessions	EAW62372 EAW62373 Q9NRR3 AF131831 AF189692 AAF87598 AI440226 AK025620 AK312406 BAG35319 BC023555 BC050430 BC058909 BC096703 AAH96703 BC096738 AAH96738 BC098349 AAH98349 BI460220 BI522591 CB135092 DA321488 NM_001038702 NP_001033791 NM_020240 NP_064625
Function	Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages. {ECO:0000269|PubMed:10816584, ECO:0000269|PubMed:15840583}.
Subcellular Location	Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor. Cell projection, phagocytic cup. Note=Recruited to the activated TCR prior actin polymerization. Localizes at the phagocytic cup of macrophages.
Tissue Specificity	Widely expressed. Expressed at higher level in T-lymphocytes. Highly expressed in CCRF-CEM T-lymphocytes, Jurkat T-lymphocytes, and Raji B-lymphocytes compared (at protein level). {ECO:0000269|PubMed:15840583}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-CDC42SE2-cDNA-Clone - DC09088 from Abgent, a WuXi AppTec company Prices $113.40 Sizes 10 µg Species Human Accession BC096703

CDC42SE2 - MBS1265826 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC096703

Human CDC42SE2 Gene ORF cDNA clone in cloning vector - HG15598-G from Sino Biological Species Human

Human CDC42SE2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15598-ACG from Sino Biological Species Human

Human CDC42SE2 Gene ORF cDNA clone expression plasmid - HG15598-UT from Sino Biological Species Human

Human CDC42SE2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15598-CF from Sino Biological Species Human

Human CDC42SE2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG15598-NY from Sino Biological Species Human

Human CDC42SE2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15598-NM from Sino Biological Species Human

Human CDC42SE2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15598-CM from Sino Biological Species Human

Human CDC42SE2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15598-ACR from Sino Biological Species Human

Human CDC42SE2 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG15598-ANR from Sino Biological Species Human

Human CDC42SE2 Gene ORF cDNA clone expression plasmid, N-His tag - HG15598-NH from Sino Biological Species Human

Human CDC42SE2 Gene ORF cDNA clone expression plasmid, C-His tag - HG15598-CH from Sino Biological Species Human

Human CDC42SE2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG15598-CY from Sino Biological Species Human

Human CDC42SE2 natural ORF mammalian expression plasmid, N-Flag tag - HG15598-NF from Sino Biological Species Human Accession BC096703

Human CDC42SE2 Gene cDNA Clone (full-length ORF Clone), expression ready, N-GFPSpark-tagged - HG15598-ANG from Sino Biological Species Human Accession BC096703

Human CDC42SE2 ORF Clone(NM_001038702.1) - CDCR343554 from Creative biogene Species Human

Human CDC42SE2 ORF Clone (BC096703) - CDCS418293 from Creative biogene Species Human Accession Q9NRR3

Human CDC42SE2 ORF clone (BC096703) - CDCB157753 from Creative biogene Species Human

Human CDC42SE2 cDNA Clone(NM_001038702.1) - CDFH003233 from Creative biogene Species Human

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