ATP2B2

Gene Symbol ATP2B2
Entrez Gene 491
Alt Symbol PMCA2, PMCA2a, PMCA2i
Species Human
Gene Type protein-coding
Description ATPase, Ca++ transporting, plasma membrane 2
Other Description plasma membrane Ca(2+)-ATPase|plasma membrane Ca2+ pump 2|plasma membrane calcium ATPase|plasma membrane calcium pump|plasma membrane calcium-transporting ATPase 2
Swissprots Q12994 Q16818 O00766 Q01814
Accessions CAP58599 EAW64079 EAW64080 EAW64081 EAW64082 EAW64083 EAW64084 Q01814 AA197323 AB210008 BAE06090 AK308898 AL134596 BC019853 BC128575 BX489007 CA391502 CK023951 DQ201777 ABG24241 DQ201778 ABG24242 L00620 AAA51893 L20977 AAA50877 M97260 AAA36456 R53305 S95738 AAA08378 S95743 AAA08377 S95758 AAA08376 U15688 AAA60985 X63575 CAA45131 XM_005265179 XP_005265236 XM_006713175 XP_006713238 XM_011533751 XP_011532053 XM_011533752 XP_011532054 XM_011533753 XP_011532055 XM_011533754 XP_011532056 XM_011533755 XP_011532057 XM_011533756 XP_011532058 XM_011533757 XP_011532059 XM_011533758 XP_011532060 XM_011533759 XP_011532061 NM_001001331 NP_001001331 NM_001683 NP_001674
Function This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell.
Subcellular Location Cell junction, synapse {ECO:0000250|UniProtKB:Q9R0K7}. Cell membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Tissue Specificity Mainly expressed in brain cortex. Found in low levels in skeletal muscle, heart muscle, stomach, liver, kidney and lung. Isoforms containing segment B are found in brain cortex and at low levels in other tissues. Isoforms containing segments X and W are found at low levels in all tissues. Isoforms containing segment A and segment Z are found at low levels in skeletal muscle and heart muscle.
Top Pathways Calcium signaling pathway, Salivary secretion, Pancreatic secretion, Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway

PMCA2 (S-18) - sc-22073 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PMCA2 (S-18): sc-22073. Immunofluorescence staining of formalin-fixed Hep G2 cells showing membrane localization.

PMCA2 (28) - sc-136043 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
PMCA2 (28): sc-136043. Western blot analysis of PMCA2 expression in rat cerebrum tissue extract.

PMCA2/3 (C-3) - sc-398013 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PMCA2/3 (C-3): sc-398013. Western blot analysis of PMCA2/3 expression in mouse brain tissue extract.

PMCA2/3 (H-112) - sc-367384 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-Calcium Pump PMCA2 ATPase antibody - ab3529 from Abcam

Prices $401.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab3529 staining Calcium Pump PMCA2 ATPase in Mouse purkinje cells in cerebellum tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with paraformaldehyde and permeabilized with 0.5% Triton X-100. Samples were incubated with primary antibody (1/500 in PBS + 3% NGS + 0.5% Triton X-100) for 16 hours at 4°C. An Alexa Fluor® 488-conjugated Goat anti-rabbit IgG monoclonal (1/500) was used as the secondary antibody.See Abreview

Anti-ATP2B2 / PMCA2 Antibody (aa5-19) - LS-C74388 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ATP2B2 / PMCA2 Antibody - LS-C341014 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PMCA / Plasma Membrane Calcium ATPase Antibody (aa724-783) - LS-C74387 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-PMCA / Plasma Membrane Calcium ATPase Antibody - LS-C87407 from LifeSpan Bioscience

Prices $515.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-PMCA / Plasma Membrane Calcium ATPase Antibody (clone CAP-6) - LS-C171051 from LifeSpan Bioscience

Prices $295.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone CAP-6

Anti-PMCA / Plasma Membrane Calcium ATPase Antibody (clone CAP-6, Magnetic beads) - LS-C171052 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone CAP-6

Anti-PMCA / Plasma Membrane Calcium ATPase Antibody (clone CAP-6, Sepharose) - LS-C171053 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone CAP-6

PMCA2 Antibody - NB120-3529 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: PMCA2 Antibody [NB120-3529] - Immunohistochemistry was performed on normal biopsies of deparaffinized Human brain tissue. To expose target proteins, heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes. Following antigen retrieval tissues were blocked in 3% BSA-PBS for 30 minutes at room temperature. Tissues were then probed at a dilution of 1:200 with a rabbit polyclonal antibody recognizing PMCA2 ATPase or without primary antibody (negative control) overnight at 4C in a humidified chamber. Tissues were washed extensively with PBST and endogenous peroxidase activity was quenched with a peroxidase suppressor. Tissues were counterstained with hematoxylin and prepped for mounting.

PMCA Polyclonal Antibody - bs-6499R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat kidney labeled with Anti-PMCA Polyclonal Antibody, Unconjugated (bs-6499R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

Anti-PMCA2 antibody produced in rabbit - P1244 from Sigma-Aldrich

Prices $334.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

ATP2B2 Antibody (OABF01698) - OABF01698 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ATP2B2 antibody - 70R-15903 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

ATP2B2 Polyclonal Antibody - A3588 from ABclonal

Prices $200.00, $480.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal

ATP2B2 Polyclonal Antibody - A6875 from ABclonal

Prices $130.00, $220.00, $380.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using ATP2B2 antibody.

ATP2B2 Antibody - abx002597 from Abbexa

Host Rabbit
Clonality Polyclonal

PMCA2 Antibody - abx007891 from Abbexa

Host Rabbit
Clonality Polyclonal

ATP2B2 / PMCA2 antibody - 19678-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical of paraffin-embedded human brain using 19678-1-AP(ATP2B2 antibody) at dilution of 1:100 (under 10x lens)

ATP2B2 / PMCA2 antibody - SP5342P from Acris Antibodies

Prices $450.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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