| Gene Symbol | AP1G1 |
|---|---|
| Entrez Gene | 164 |
| Alt Symbol | ADTG, CLAPG1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | adaptor-related protein complex 1, gamma 1 subunit |
| Other Description | AP-1 complex subunit gamma-1|adapter-related protein complex 1 subunit gamma-1|adaptor protein complex AP-1 subunit gamma-1|adaptor-related protein complex 1 subunit gamma-1|clathrin assembly protein complex 1 gamma large chain|clathrin assembly protein complex 1 gamma-1 large chain|clathrin-associated/assembly/adaptor protein, large, gamma 1|gamma adaptin|gamma1-adaptin|golgi adaptor HA1/AP1 adaptin gamma subunit|golgi adaptor HA1/AP1 adaptin subunit gamma-1 |
| Swissprots | Q9UG09 O43747 Q9Y3U4 O75842 O75709 |
| Accessions | CAA11832 EAW59222 EAW59223 EAW59224 O43747 AB015317 BAA33389 AK025020 AK055122 BAG51473 AK128078 BAG54627 AK225906 AK293233 BAG56772 AK294546 BAG57752 AK299630 BAG61558 AK314484 AL110198 CAB53673 BC003414 AAH03414 BC036283 AAH36283 BC051747 BU902252 EU832486 ACE87658 EU832566 ACE86968 Y12226 CAA72902 NM_001030007 NP_001025178 NM_001128 NP_001119 |
| Function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. |
| Subcellular Location | Golgi apparatus {ECO:0000269|PubMed:12773381}. Cytoplasmic vesicle, clathrin- coated vesicle membrane {ECO:0000269|PubMed:12773381}; Peripheral membrane protein {ECO:0000269|PubMed:12773381}; Cytoplasmic side {ECO:0000269|PubMed:12773381}. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. |
| Tissue Specificity | Widely expressed. |
| Top Pathways | Lysosome |