| Gene Symbol |
GNG4
|
| Entrez Gene |
2786
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
guanine nucleotide binding protein (G protein), gamma 4
|
| Other Description |
guanine nucleotide binding protein 4|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
|
| Swissprots |
P50150
|
| Accessions |
CBX47432 CBX47433 CBX47434 EAW70030 EAW70031 P50150 AF493872 AAM12586 AK074383 AK311781 BAG34724 AL832564 BC022485 AAH22485 CX784976 DA122711 DA230013 DB501745 U31382 AAC50204 XM_006711761 XP_006711824 XM_011544165 XP_011542467 XM_011544166 XP_011542468 XM_011544167 XP_011542469 XM_011544168 XP_011542470 NM_001098721 NP_001092191 NM_001098722 NP_001092192 NM_004485 NP_004476
|
| Function |
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
|
| Subcellular Location |
Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
|
| Tissue Specificity |
Brain, kidney, pancreas, skeletal muscle and faintly in cardiac muscle.
|
| Top Pathways |
Dopaminergic synapse, Morphine addiction, Glutamatergic synapse, PI3K-Akt signaling pathway, GABAergic synapse
|