| Gene Symbol | CELE_Y69A2AR.5 |
|---|---|
| Entrez Gene | 3565775 |
| Alt Symbol | - |
| Species | C. elegans |
| Gene Type | protein-coding |
| Description | DAAO-1 |
| Other Description | - |
| Swissprots | Q95XG9 |
| Accessions | CCD74112 Q95XG9 AB275890 BAF34313 NM_067833 NP_500234 |
| Function | Catalyzes oxidative deamination of D-amino acids, in particular D-alanine, and could be responsible for the degradation of diet-derived D-alanine in the intestine. Acts on a variety of D-amino acids with greater preference towards those with basic and aromatic groups followed by those bearing neutral groups. Has no activity against acidic D-amino acids, L-amino acids or N-methyl- L-aspartic acid. May play a role in egg-laying events and early development. {ECO:0000269|PubMed:17140416, ECO:0000269|PubMed:20564561, ECO:0000269|PubMed:22393259}. |
| Subcellular Location | Peroxisome {ECO:0000269|PubMed:17140416, ECO:0000305}. |
| Tissue Specificity | Expressed exclusively in the intestine. {ECO:0000269|PubMed:22393259}. |
| Top Pathways | Glycine, serine and threonine metabolism, Peroxisome, Arginine and proline metabolism, D-Arginine and D-ornithine metabolism |