RAET1E

Gene Symbol	RAET1E
Entrez Gene	135250
Alt Symbol	LETAL, N2DL-4, NKG2DL4, RAET1E2, RL-4, ULBP4, bA350J20.7
Species	Human
Gene Type	protein-coding
Description	retinoic acid early transcript 1E
Other Description	NKG2D ligand 4|RAE-1-like transcript 4|lymphocyte effector toxicity activation ligand
Swissprots	Q8TD07 Q5VYB7 A6YF59 Q96L41 Q5VYB8 Q8TEZ2
Accessions	AFP19431 AFP19432 AFP19433 AFP19434 AFP19435 AFP19436 AFP19437 CCH35985 CCH35986 CCH57703 CCH57704 CCH57705 CCH57706 CCH57707 CCH57708 EAW47781 EAW47782 EAW47783 Q8TD07 AF359243 AAL76417 AY054974 AAL11005 AY069961 AAL58090 AY176317 AAO22240 AY252119 AAP15166 AY359075 AAQ89434 BC101976 AAI01977 BC103694 AAI03695 EF489426 ABR29881 KJ628092 AIC38369 XM_011535475 XP_011533777 XM_011535476 XP_011533778 XM_011535477 XP_011533779 XM_011535478 XP_011533780 XM_011535479 XP_011533781 XR_942296 XR_942297 XR_942298 NM_001243325 NP_001230254 NM_001243327 NP_001230256 NM_001243328 NP_001230257 NM_139165 NP_631904
Function	Ligand for the KLRK1 receptor. Delivers activating signals to NK cells and promotes tumor immune surveillance by inducing the expansion of anti-tumor cytotoxic lymphocytes.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Predominantly expressed in the skin, but also expressed in testis and trachea. Up-regulated in tumor cells of different origins. Expression progressively decreased after treatment of tumor cells with retinoic acid. {ECO:0000269|PubMed:12732206, ECO:0000269|PubMed:14508119}.
Top Pathways	Natural killer cell mediated cytotoxicity

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ULBP4 protein fragment - ab137171 from Abcam Category Protein Source E. coli Species Human

NKG2DL4 / ULBP4 Antibody Blocking Peptide - LS-E6706 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NKG2DL4 / ULBP4 Antibody Blocking Peptide - LS-E23760 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ULBP-4/RAET1E Partial Recombinant Protein - H00135250-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

ULBP-4/RAET1E Recombinant Protein - H00135250-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human ULBP-4/RAET1E Protein - NBP2-23410 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

RAET1E-AntibodyCenter-Blocking-peptide - BP19552c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human ULBP-4/RAET1E Fc Chimera, CF - 6285-UL-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Human ULBP4 (His Tag) protein - orb179697 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Cells Species Human

Human ULBP4 (Fc Tag) protein - orb179696 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Cells Species Human

RAET1E protein (His tag) - 80R-2598 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

RAET1E (31-225, His-tag) - AR50644PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

RAET1E (31-225, His-tag) - AR50644PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

RAET1E - H00135250-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RAET1E - H00135250-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

RAET1E - H00135250-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RAET1E - H00135250-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

RAET1E, 31-225 aa, Human, His tag, E.coli - 01-P1820 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

RAET1E Peptide - 8193P from ProSci Category Peptide Species Human

RAET1E fusion protein - ag16087 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

RAET1E fusion protein - ag17278 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

RAET1E Human - PRPS-1300 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human retinoic acid early transcript 1E, His-tagged - RAET1E-381H from Creative Biomart Category Protein Source E.coli Species Human

Human RAET1E / ULBP4 Protein (Fc Tag) - 16073-H02H-100 from Sino Biological Category Protein Prices $178.00, $298.00 Sizes 50 µg, 100 µg Source Human Cells Species Human

Human RAET1E / ULBP4 Protein (His Tag) - 16073-H08H-100 from Sino Biological Category Protein Prices $178.00, $298.00 Sizes 50 µg, 100 µg Source Human Cells Species Human

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