FPR2

Gene Symbol FPR2
Entrez Gene 2358
Alt Symbol ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, HM63, LXA4R
Species Human
Gene Type protein-coding
Description formyl peptide receptor 2
Other Description FMLP-R-I|FMLP-related receptor I|LXA4 receptor|N-formyl peptide receptor 2|RFP|formyl peptide receptor-like 1|lipoxin A4 receptor (formyl peptide receptor related)
Swissprots A8K3E2 P25090
Accessions AAB23104 AAF87844 AAO67711 EAW72043 EAW72044 P25090 AF054013 AAC13684 AK290557 BAF83246 BC029125 AAH29125 BC071722 AAH71722 BM922150 D10922 BAA01720 DQ892105 ABM83031 DQ895299 ABM86225 M76672 AAA58481 M84562 AAA52473 M88107 AAA60070 U81501 AAB51133 X63819 CAA45319 XM_006723120 XP_006723183 NM_001005738 NP_001005738 NM_001462 NP_001453
Function Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis. {ECO:0000269|PubMed:9151906}.
Top Pathways Staphylococcus aureus infection, Neuroactive ligand-receptor interaction

FPR2 (C-17) - sc-13194 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FPR2 (C-17): sc-13194. Western blot analysis of FPRL1 expression in non-transfected: sc-117752 (A) and human FPRL1 transfected: sc-117318 (B) 293T whole cell lysates.

FPR2 (F-16) - sc-13193 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

FPR2 (GM1D6) - sc-57141 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FPR2 (GM1D6): sc-57141. Western blot analysis of FPR2 expression in human PBL (A) and AML-193 (B) whole cell lysates under non-reducing conditions.

FPR2 (H-150) - sc-66898 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
FPR2 (H-150): sc-66898. Western blot analysis of FPR2 expression in AML-193 whole cell lysate.

FPR2/3 (N-20)-R - sc-18191-R from Santa Cruz Biotechnology

Prices $61.00
Sizes 100 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
FPR2/3 (N-20)-R: sc-18191-R. Immunoperoxidase staining of formalin fixed, paraffin-embedded human rectum tissue showing cytoplasmic and membrane staining of glandular cells.

Anti-FPRL1 antibody - ab63022 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-FPRL1 antibody (ab63022) at 1/5000 dilution + Extracts from HL60 cells.

Anti-FPRL1 antibody - ab101702 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab101702 stained WI 38 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab101702 at 1/200 dilution overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-FPRL1 antibody - ab63023 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-FPRL1 antibody (ab63023) at 1/6000 dilution + Extracts of HL60 cells

Anti-FPRL1 antibody [GM1D6] - ab26316 from Abcam

Prices $382.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone GM1D6
ab26316 staining of FPRL1 in CHO cells using 1µg/106 cells. CHO cells were transiently transfected with an expession vector encoding FPRL1 and binding of ab26316 was visualized using a FITC-conjugated secondary antibody (green). Actin filaments are labelled with Alexa Fluor-55 Phalloidin (red). Cell nuclei are stained with DAPI (blue).

Anti-FPR2 / FPRL1 Antibody - LS-C66268 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence labeling of HL-60 cells using LS-C66268 (green). Nuclei have been labeled with PI (red).

Anti-FPR2 / FPRL1 Antibody (C-Terminus) IHC-plus™ - LS-B2911 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-FPR2 / FPRL1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2911 concentration 5 ug/ml.

Anti-FPR2 / FPRL1 Antibody (aa13-26) - LS-C54876 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-FPR2 / FPRL1 Antibody (aa328-339) - LS-C54877 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-FPR2 / FPRL1 Antibody - LS-C92547 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-FPR2 / FPRL1 Antibody (aa181-192) - LS-C125624 from LifeSpan Bioscience

Prices $465.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal

Anti-FPR2 / FPRL1 Antibody (aa181-192) - LS-C125625 from LifeSpan Bioscience

Prices $465.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal

Anti-FPR2 / FPRL1 Antibody (DY650) - LS-C182025 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-FPR2 / FPRL1 Antibody (Biotin) - LS-C182024 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-FPR2 / FPRL1 Antibody (DY488) - LS-C182026 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-FPR2 / FPRL1 Antibody (HRP) - LS-C182027 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-FPR2 / FPRL1 Antibody (DY550) - LS-C182028 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-FPR2 / FPRL1 Antibody (N-Terminus) IHC-plus™ - LS-A1880 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-FPR2 / FPRL1 antibody IHC of human spleen, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A1880 dilution 20-40 ug/ml.

Anti-FPR2 / FPRL1 Antibody - LS-C310400 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-FPR2 / FPRL1 Antibody - LS-C310402 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FPR2 / FPRL1 Antibody (clone 2D8) - LS-C197242 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2D8
FPR2 monoclonal antibody (M02), clone 2D8. Western Blot analysis of FPR2 expression in HeLa NE.
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