FPR2

Gene Symbol FPR2
Entrez Gene 2358
Alt Symbol ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, HM63, LXA4R
Species Human
Gene Type protein-coding
Description formyl peptide receptor 2
Other Description FMLP-R-I|FMLP-related receptor I|LXA4 receptor|N-formyl peptide receptor 2|RFP|formyl peptide receptor-like 1|lipoxin A4 receptor (formyl peptide receptor related)
Swissprots A8K3E2 P25090
Accessions AAB23104 AAF87844 AAO67711 EAW72043 EAW72044 P25090 AF054013 AAC13684 AK290557 BAF83246 BC029125 AAH29125 BC071722 AAH71722 BM922150 D10922 BAA01720 DQ892105 ABM83031 DQ895299 ABM86225 M76672 AAA58481 M84562 AAA52473 M88107 AAA60070 U81501 AAB51133 X63819 CAA45319 XM_006723120 XP_006723183 NM_001005738 NP_001005738 NM_001462 NP_001453
Function Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis. {ECO:0000269|PubMed:9151906}.
Top Pathways Staphylococcus aureus infection, Neuroactive ligand-receptor interaction

FPR2 CRISPR/Cas9 KO Plasmid (h) - sc-401738 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FPR2 HDR Plasmid (h) - sc-401738-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FPR2 Double Nickase Plasmid (h) - sc-401738-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FPR2 Double Nickase Plasmid (h2) - sc-401738-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FPR2 CRISPR Activation Plasmid (h) - sc-401738-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FPR2 CRISPR Activation Plasmid (h2) - sc-401738-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FPR2 Lentiviral Activation Particles (h) - sc-401738-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FPR2 Lentiviral Activation Particles (h2) - sc-401738-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FPR2 siRNA (h) - sc-40123 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FPR2 shRNA Plasmid (h) - sc-40123-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FPR2 shRNA (h) Lentiviral Particles - sc-40123-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FPRL1/FPR2 RNAi - H00002358-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

FPRL1/FPR2 RNAi - H00002358-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU017941 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8927 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8927 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07422 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07422

FPR2 siRNA (Human) - CRH1649 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FPR2 - MBS8211043 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FPR2 (NM_001462.3) - SHH296953 from Creative biogene

Category siRNA
Species Reactivities Human

FPR2 shRNA Plasmid (Human) - CHH1649 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FPR2 miRNA 3'UTR clone - MiUTR1H-03843 from Creative biogene

Species Reactivities Human

FPR2 miRNA 3'UTR clone - MiUTR3H-00830 from Creative biogene

Species Reactivities Human
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