| Gene Symbol |
Cyp2e1
|
| Entrez Gene |
13106
|
| Alt Symbol |
Cyp2e
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
cytochrome P450, family 2, subfamily e, polypeptide 1
|
| Other Description |
4-nitrophenol 2-hydroxylase|CYPIIE1|cytochrome P450 2E1|cytochrome P450, 2e1, ethanol inducible|cytochrome P450-ALC|cytochrome P450-J
|
| Swissprots |
Q9Z198 Q05421
|
| Accessions |
EDL17941 EDL17942 EDL17943 EDL17944 EDL17945 EDL17946 Q05421 BC013451 AAH13451 BC042693 DQ838976 ABH07947 DQ838977 ABH07948 L11650 AAA39879 M27582 M54877 AAA37275 X01026 CAA25510 X62595 CAA44481 NM_021282 NP_067257
|
| Function |
Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. {ECO:0000250}.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
|
| Tissue Specificity |
Highest level in the liver and to a lesser extent in the kidney, with a higher level in the male kidney than in the female.
|
| Top Pathways |
Steroid hormone biosynthesis, Chemical carcinogenesis, Non-alcoholic fatty liver disease (NAFLD), Arachidonic acid metabolism, Linoleic acid metabolism
|