Gene Symbol | SOX1 |
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Entrez Gene | 6656 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | SRY (sex determining region Y)-box 1 |
Other Description | SRY-related HMG-box gene 1|transcription factor SOX-1 |
Swissprots | O00570 Q5W0Q1 |
Accessions | CAA73847 EAX09158 O00570 NM_005986 NP_005977 |
Function | Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Mainly expressed in the developing central nervous system. |
Sox-1 CRISPR/Cas9 KO Plasmid (h) - sc-401473 from Santa Cruz Biotechnology
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Sox-1 HDR Plasmid (h) - sc-401473-HDR from Santa Cruz Biotechnology
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Sox-1 Double Nickase Plasmid (h) - sc-401473-NIC from Santa Cruz Biotechnology
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Sox-1 Double Nickase Plasmid (h2) - sc-401473-NIC-2 from Santa Cruz Biotechnology
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Sox-1 CRISPR Activation Plasmid (h) - sc-401473-ACT from Santa Cruz Biotechnology
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Sox-1 CRISPR Activation Plasmid (h2) - sc-401473-ACT-2 from Santa Cruz Biotechnology
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Sox-1 Lentiviral Activation Particles (h) - sc-401473-LAC from Santa Cruz Biotechnology
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Sox-1 Lentiviral Activation Particles (h2) - sc-401473-LAC-2 from Santa Cruz Biotechnology
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Sox-1 siRNA (h) - sc-38406 from Santa Cruz Biotechnology
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Sox-1 shRNA Plasmid (h) - sc-38406-SH from Santa Cruz Biotechnology
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Sox-1 shRNA (h) Lentiviral Particles - sc-38406-V from Santa Cruz Biotechnology
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SOX1 RNAi - H00006656-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN20346 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20346 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12975 from Sigma-Aldrich
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SOX1 siRNA (Human) - CRH4536 from Cohesion Biosciences
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SOX1 - MBS8217957 from MyBioSource
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shRNA set against Human SOX1 (NM_005986.2) - SHH415256 from Creative biogene
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shRNA set against Human SOX1(NM_005986.2) - SHL016986 from Creative biogene
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Human SOX1 siRNA - orb265038 from Biorbyt
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SOX1 shRNA Plasmid (Human) - CHH4536 from Cohesion Biosciences
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SOX1 miRNA 3'UTR clone - MiUTR1H-09758 from Creative biogene
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