| Gene Symbol |
CSRNP1
|
| Entrez Gene |
64651
|
| Alt Symbol |
AXUD1, CSRNP-1, FAM130B, TAIP-3, URAX1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cysteine-serine-rich nuclear protein 1
|
| Other Description |
AXIN1 up-regulated 1|TGF-beta induced apoptosis protein 3|TGF-beta-induced apoptosis protein 3|axin-1 up-regulated gene 1 protein|cysteine/serine-rich nuclear protein 1
|
| Swissprots |
Q96S65 Q69YY5
|
| Accessions |
CAD12290 CCQ43790 EAW64565 EAW64566 EAW64567 EAW64568 EAW64569 EAW64570 Q96S65 AB053121 BAB61065 AB063301 BAB79450 AL117565 CAH10719 BC028213 AAH28213 BC038949 AAH38949 BG536908 XM_005265403 XP_005265460 XM_011534019 XP_011532321 NM_033027 NP_149016
|
| Function |
Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity (By similarity). May have a tumor-suppressor function. May play a role in apoptosis. {ECO:0000250, ECO:0000269|PubMed:11526492}.
|
| Subcellular Location |
Nucleus {ECO:0000250}.
|
| Tissue Specificity |
Ubiquitous. Most abundantly expressed in lung, placenta, skeletal muscle, pancreas and leukocyte. Frequently down-regulated in lung, kidney, liver and colon cancers compared with their corresponding normal tissues. {ECO:0000269|PubMed:11526492}.
|
![Western Blot: AXUD1 Overexpression Lysate (Adult Normal) [NBL1-07870] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for AXUD1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4028_AXUD1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07870-img0002.jpg)