CALCOCO1

Gene Symbol CALCOCO1
Entrez Gene 57658
Alt Symbol Cocoa, PP13275, calphoglin
Species Human
Gene Type protein-coding
Description calcium binding and coiled-coil domain 1
Other Description calcium-binding and coiled-coil domain-containing protein 1|coiled-coil coactivator protein|coiled-coil leucine zipper coactivator 1|inorganic pyrophosphatase activator|sarcoma antigen NY-SAR-3
Swissprots Q9H090 Q71RC3 Q9P1Z2 Q96JU3 Q86WF8 Q6FI59 B3KVA8
Accessions EAW96727 EAW96728 EAW96729 EAW96730 EAW96731 EAW96732 EAW96733 Q9P1Z2 AB040969 BAA96060 AF370415 AAQ15251 AK027881 BAB55428 AK092788 BAG52609 AK122773 BAG53720 AK222646 AK294424 BAG57671 AK296497 BAG59131 AK309199 AK315578 AL136895 CAB66829 AM393253 CAL38131 AY211909 AAO65163 AY358397 AAQ88763 AY563137 AAT68474 BC003177 AAH03177 BX538208 CAD98068 CD723746 CR533567 CAG38598 DB060684 XM_011538601 XP_011536903 XM_011538602 XP_011536904 XM_011538603 XP_011536905 XM_011538604 XP_011536906 NM_001143682 NP_001137154 NM_020898 NP_065949 NR_026554
Function Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR). Recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS) domain of transcription factors or coactivators, such as NCOA2. During ER-activation acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. Involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. Functions as a secondary coactivator in LEF1- mediated transcriptional activation via its interaction with CTNNB1. Coactivator function for nuclear receptors and LEF1/CTNNB1 involves differential utilization of two different activation regions (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm. Nucleus. Note=Shuttles between nucleus and cytoplasm. {ECO:0000250}.

CALCOCO1 (D-20) - sc-161423 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CALCOCO1 (N-14) - sc-161424 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CALCOCO1 (N-14): sc-161424. Western blot analysis of CALCOCO1 expression in HEK293 (A) and Ramos (B) whole cell lysates and HeLa nuclear extract (C).

Anti-CoCoA antibody - ab70564 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CoCoA antibody (ab70564) at 0.4 µg/mlLane 1 : HeLa whole cell lysateLane 2 : 293T whole cell lysateLane 3 : NIH3T3 whole cell lysateLane 4 : Ramos whole cell lysateLane 5 : MCF7 whole cell lysateLysates/proteins at 50 µg per lane.developed using the ECL technique

Anti-CoCoA antibody - ab154731 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CoCoA antibody (ab154731) at 1/500 dilution + HeLaS3 whole cell lysate at 30 µg

Anti-CoCoA antibody - ab167237 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-CoCoA antibody (ab167237) at 1 µg/ml + Rat brain tissue lysate at 50 µgSecondaryGoat anti-Mouse IgG HRP at 1/2500 dilution

Anti-CoCoA antibody - ab70563 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of human CoCoA by Immunoprecipitation in whole cell lysate from MCF7 cells (1 mg, 20% of immunoprecipitate loaded/lane), using ab70563 at 3 µg/mg of lysate (lane 1). CoCoA was also immunoprecipitated using another CoCoA antibody (ab70564) which recognizes a downstream epitope (lane 2). Lane 3: Control IgG immunoprecipitate. Subsequent blotting of immunoprecipitate for the detection of CoCoA was performed using 1µg/ml of the other antibody (ab70564) and 50µg of lysate. Detection was by chemiluminescence with an exposure time of 30 seconds.

Anti-CALCOCO1 / CoCoa Antibody (aa1-50) - LS-C286211 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CALCOCO1 / CoCoa Antibody (C-Terminus) - LS-C287672 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CALCOCO1 / CoCoa Antibody (aa71-120) - LS-C116681 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CALCOCO1 / CoCoa antibody LS-C116681 Western blot of Jurkat lysate.

CoCoA Antibody - NBP1-88216 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CoCoA Antibody [NBP1-88216] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

CoCoA Antibody - NBP1-88215 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CoCoA Antibody - NBP1-32154 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CoCoA Antibody [NBP1-32154] - Sample(30 ug of whole cell lysate) A:HeLa S3 7.5% SDS PAGE, antibody diluted at 1:500.

CoCoA Antibody - H00057658-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: CoCoA Antibody [H00057658-B01P] - Analysis of CALCOCO1 expression in rat brain.

Anti-CALCOCO1 antibody produced in mouse - SAB1409580 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CALCOCO1: <B>Cat. No. SAB1409580</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~77.3 kDa using rat brain lysate.

Anti-CALCOCO1, (N-terminal) antibody produced in rabbit - SAB2106122 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CALCOCO1 (N-Terminal): <B>Cat. No. SAB2106122</B>: CALCOCO1 in Jurkat cell lysates with CALCOCO1 antibody at 1.0 μg/mL.

Anti-CALCOCO1 (511-525) antibody produced in rabbit - SAB1104656 from Sigma-Aldrich

Prices $285.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CALCOCO1 antibody produced in rabbit - HPA038314 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CALCOCO1: <B>Cat. No. HPA038314</B>: Immunohistochemical staining of human breast shows strong cytoplasmic positivity in glandular cells.

Anti-CALCOCO1 antibody produced in rabbit - HPA038313 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CALCOCO1: <B>Cat. No. HPA038313</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules and cells in glomeruli.

CALCOCO1 antibody - N-terminal region (ARP57483_P050) - ARP57483_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CoCoA antibody [N2C2], Internal - GTX105118 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-CoCoA antibody [N2C2], Internal used in IHC (Formalin-fixed paraffin-embedded sections). GTX105118

CALCOCO1 antibody - 70R-16127 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

CALCOCO1 antibody - 19843-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical of paraffin-embedded human testis using 19843-1-AP(CALCOCO1 antibody) at dilution of 1:100 (under 10x lens)

CALCOCO1 antibody - H00057658-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

CALCOCO1 antibody - 19843-1-AP from Proteintech Group

Prices $279.00
Sizes con: 20 μg/150μl
Host Rabbit
Clonality Polyclonal
HT-1080 cells were subjected to SDS PAGE followed by western blot with 19843-1-AP(CALCOCO1 antibody) at dilution of 1:400

calcium binding and coiled-coil domain 1 , Polyclonal Antibody - MBS714414 from MyBioSource

Prices $230.00, $500.00
Sizes 50 µl, 150 µl
Host Rabbit
Clonality Polyclonal
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