| Gene Symbol |
B4GALNT3
|
| Entrez Gene |
283358
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
beta-1,4-N-acetyl-galactosaminyl transferase 3
|
| Other Description |
B4GalNAcT3|Beta4GalNAc-T3|N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase|N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2|NGalNAc-T2|beta-1,4-N-acetylgalactosaminyltransferase 3|beta-1,4-N-acetylgalactosaminyltransferase III|beta4GalNAcT3
|
| Swissprots |
Q6L9W6 Q8N7T6 Q6ZNC1
|
| Accessions |
EAW88962 EAW88963 EAW88964 EAW88965 Q6L9W6 AB089940 BAD02449 AK093503 BAC04187 AK097681 BAC05141 AK131277 BAD18454 BC156653 AAI56654 CN400443 NM_173593 NP_775864
|
| Function |
Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. Mediates the N,N'- diacetyllactosediamine formation on gastric mucosa. {ECO:0000269|PubMed:16728562}.
|
| Subcellular Location |
Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:16728562}; Single-pass type II membrane protein {ECO:0000269|PubMed:16728562}. Note=Localizes to apical Golgi.
|
| Tissue Specificity |
Highly expressed in testis, colon and stomach. Weakly expressed in other tissues. {ECO:0000269|PubMed:12966086}.
|