| Gene Symbol | GNB2 |
|---|---|
| Entrez Gene | 2783 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | guanine nucleotide binding protein (G protein), beta polypeptide 2 |
| Other Description | G protein, beta-2 subunit|g protein subunit beta-2|guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 2|guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2|signal-transducing guanine nucleotide-binding regulatory protein beta subunit|transducin beta chain 2 |
| Swissprots | B3KPU1 P62879 P54312 P11016 |
| Accessions | AAA03179 EAW76499 EAW76500 EAW76501 P62879 AF064853 AF501883 AAM15919 AK056750 BAG51803 AK291592 BAF84281 AL535249 BC010073 AAH10073 BC012348 AAH12348 BC068003 AAH68003 BM763069 CR541729 CAG46530 CV569909 HQ448251 ADQ32731 JF432644 ADZ15861 M16538 AAA35922 M36429 AAA63264 NM_005273 NP_005264 |
| Function | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. |
| Subcellular Location | Cytoplasm, perinuclear region {ECO:0000269|PubMed:16498633}. |
| Top Pathways | Dopaminergic synapse, Morphine addiction, Glutamatergic synapse, PI3K-Akt signaling pathway, GABAergic synapse |